It has been two years since clinical development of cancer immunotherapy has started to turn from decades of failures to its first successes in randomized Phase 3 trials with Sipuleucel-T, a dendritic cellbased vaccine, and ipilimumab, a monoclonal antibody targeting CTLA-4. Both are increasing patient survival in their target diseases. The path to these successes was, in part, paved by the met...

BACKGROUND Visit preparation interventions help patients prepare to meet with a medical provider. Systematic reviews have found some positive effects, but there are no reports describing implementation experiences. Consultation Planning (CP) is a visit preparation technique in which a trained coach or facilitator elicits and documents patient questions for an upcoming medical appointment. We in...

Significant racial, socioeconomic, and geographic disparities exist nationwide in cancer screenings, treatments, and outcomes. Differences in health and social service provision and utilization may contribute to or exacerbate these disparities. We evaluated the composition and structure of a referral network of organizations providing services to underserved cancer patients in an urban area in ...

although splenic metastasis is fairly common in disseminated cancer, solitary splenic metastasis in the absence of diffuse dissemination is rare. we report a case of 44 year-old man who developed isolated splenic metastasis of colon cancer. the patient had undergone right sided hemicolectomy for colon cancer in 1988. in 2001, he underwent reoperation because of local recurrence of tumor in the ...

introduction: breast cancer is the second most common cause of brain metastasis. although patient prognosis is poor, isolated brain metastasis occasionally can be an option for treatment with curative intent in breast cancer patients. case presentation: we report a patient with invasive ductal carcinoma of the breast who developed an isolated right frontal lobe metastasis within 5 months of fin...