A new peptide antibiotic, cypemycin, with a molecular weight of 2,097 (M+H), was isolated from the culture broth of Streptomyces sp. OH-4156. The antibiotic possesses cytocidal activity against P388 leukemia cells in vitro at a concentration of 1.3 microgram/ml (IC50 values), and the antibiotic showed antimicrobial activities against Micrococcus luteus (MIC, 0.2 microgram/ml).

Our understanding of within-species annual plant adaptation to rainfall gradients is fragmented. Broad-scale ecological applications of Grime's C-S-R triangle are often superficial, while detailed drought physiology tends to be narrow, focusing on elite cultivars. The former lack the detail to explain how plants respond, while the latter provide little context to investigate trade-offs among tr...

The cleavage of a DNA phosphodiester bond by Escherichia coli DNA topoisomerase I and the simultaneous covalent linkage of the enzyme to the 5’-phosphoryl group of the DNA at the cleavage site have been reported previously (Depew, R. E., Liu, L. F., and Wang, J. C. (1978) J. Biol. Chem 253, 511-518; Liu, L. F., and Wang, J. C. (1979) J. Biol. Chem 254, 11082-11088). With either E. coli or Micmc...

BACKGROUND Stethoscope diaphragms have been shown to harbor potentially pathogenic bacteria. OBJECTIVES To assess bacterial contamination on the diaphragm and under the plastic rim that secures the diaphragm of stethoscopes of physicians, nurses, medical students, and house staff in an intensive care unit and a general medical ward of a large university hospital. Also to compare the effective...

Micrococcus luteus naturally produces alkenes, unsaturated aliphatic hydrocarbons, and represents a promising host to produce hydrocarbons as constituents of biofuels and lubricants. In this work, we identify the genes for key enzymes of the branched-chain amino acid catabolism in M. luteus, whose first metabolic steps lead also to the formation of primer molecules for branched-chain fatty acid...

Microbial stress due to the impaction of microorganisms onto an agar collection surface was studied experimentally. The relative recovery rates of aerosolized Pseudomonas fluorescens and Micrococcus luteus were determined as a function of the impaction velocity by using a moving agar slide impactor operating over a flow rate range from 3.8 to 40 liters/min yielding impaction velocities from 24 ...

Cyanobacteria can play an important role in sustainable agriculture by improving crop growth and production, as well environmental quality. The current study was conducted to evaluate the of Spirulina platensis extract improvement growth, photosynthetic capacity yield Lupinus luteus. Different concentrations (0.25, 0.5 1.0%) S. methanolic were used for priming seeds foliar spraying applications...

Hospital infections (HI) are a serious public health problem in many countries. Several studies have identified strains correlating to surgical site infections, with multi-resistance. The goals of this study was quantify, identify and verify the resistance profile microorganisms collected at two hospitals settings, alert professionals how environmental contamination can influence hospital infec...

The present study aims to identify and quantify the edible mushroom with high production value in Pinus radiata forests, their natural as an ecosystem service for peasant communities of Cuyuni Yuracmayo district Ccatca (Cusco, Peru). Fifty fungal samples were collected according cap diameter (10 cm, 15 cm 20 cm), counting taxonomic identification. 5 forests different growth ages (forest younger...