PURPOSE The carcinoid tumor was recently categorized as a malignant disease due to its possibility of metastasis. This study was aimed to investigate the clinical characteristics and the metastatic rate of colorectal carcinoid tumors. METHODS Charts were reviewed for 502 patients diagnosed with and treated for colorectal carcinoid tumors between January 2006 and December 2009. The location, s...

Carcinoid is one of the most common tumors of the gastrointestinal tract followed by the tracheobronchial tree. Bronchial carcinoid compromises 20% of total carcinoid and accounts for 1-5% of pulmonary malignancies. Carcinoid can be typical or atypical, with atypical carcinoid compromises 10% of the carcinoid tumors. Carcinoid usually presents as peripheral lung lesion or solitary endobronchial...

There are three main areas of origin for carcinoid tumors: foregut carcinoid tumours start in the lungs, bronchi, or stomach; midgut carcinoid tumours start in the small intestine, appendix, or proximal large bowel; and hindgut carcinoid tumours start in the distal colon or rectum3. The appendix is the most common site of carcinoid tumors, followed by the rectum, ileum, lungs, bronchi, and stom...

BACKGROUND Carcinoid tumors of the duodenum are rare, and their natural history has not been defined. Consequently, there is no consensus on the optimal extent of surgical treatment. METHODS The authors reviewed the records of all patients with primary carcinoid tumors of the duodenum treated at their institution from 1969 through 2004. Patients with primary periampullary tumors and gastrinom...

Background: The purpose of this study was to evaluate the clinical, biological and radiological responses to, tolerability of, conventional transarterial chemoembolization (cTACE) using streptozocin for unresectable neuroendocrine liver metastases. Patients Methods: A total 52 patients with predominant disease were treated cTACE an emulsion streptozocin, Lipiodol embolization particles. sequent...

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BACKGROUND Carcinoid tumor, benign, low-grade malignant, and high-grade malignant, can be associated with the release of vasoactive substances that cause symptoms including cutaneous flushing, diarrhea, and bronchospasm. In 50-60% of patients with carcinoid syndrome, the vasoactive substances cause fibrosis of the pulmonary and tricuspid heart valves which lead to regurgitation and right-sided ...

A woman aged 46 was found to have severe tricuspid valve disease 14 years after the diagnosis of a malignant carcinoid tumour of the ileum and 33 years after the onset of symptoms attributable to the disease. Increasing ascites requiring repeated paracentesis had not responded to chemotherapy including infusion of 5-fluorouracil and vincristine into the coeliac artery. The tricuspid valve was r...

DESCRIPTION These are images of an elderly man presenting with back pain, weight loss and diarrhoea. Clinical examination revealed peripheral oedema, pan-systolic murmur and a nontender mass in his left iliac fossa. Abdominal CT revealed a calcified mass in the left iliac fossa with a characteristic spoke wheel appearance of carcinoid tumour (see arrow in figure 1) and solid and cystic liver le...

The cardiac manifestations of a neuroendocrine tumour are referred to as carcinoid heart disease (CaHD) and are associated with a poor prognosis. Surgical intervention is the only proven therapeutic option and may prolong survival and quality of life. No consensus has been reached internationally with regard to screening for CaHD and the optimal timing for surgery. Although limited evidence is ...