Objective: In cardiovascular diseases, inflammatory response plays an important role and affects heart function. As a flavonoid compound, p-coumaric acid (pCA), commonly exists in many fruits and vegetables and has a therapeutic effect on inflammatory diseases due to its anti-inflammatory properties. The purpose of the present study was to investigate pCA anti-inflammatory effect and the miRNAs...

conclusions with a thorough preoperative assessment incorporating focused echocardiography, anaesthetists are in the unique position to enhance their role as perioperative physicians and influence short and long term outcomes of their patients. context patients with undifferentiated systolic murmurs present commonly during the perioperative period. traditional bedside assessment and auscultatio...

MicroRNAs (miRs) are endogenous ≈22-nt non-coding RNAs that participate in the regulation of gene expression at post-transcriptional level. MiR-1 is one of the muscle-specific miRs, aberrant expression of miR-1 plays important roles in many physiological and pathological processes. In this review, we focus on the recent studies about miR-1 in cardiac diseases and cancers. The findings indicate ...

Cardiac diseases complicate 1% to 4% of pregnancies in women without preexisting cardiac abnormalities. A working knowledge of the normal physiology of pregnancy is often helpful in the management of patients with heart disease. Patients with preexisting cardiac lesions should be counseled in advance about the risk of pregnancy. Familiarity with the treatment of commonly encountered cardiac dis...

It has been observed that the incidence of heart failure and Brugada syndrome are higher in men, while women are more likely to have QT interval prolongation and develop torsades de pointes (TdP). Over the past decade, new studies have improved our understanding of the mechanisms of abnormal repolarization and the relationship between gender differences in cardiac repolarization and presentatio...

Southern General Hospital has prevented any systematic lIivestigation into the cardiac disturbances and lesions that have been encountered. Nevertheless, it may be worth wnile to report the most definite impressions that these Matters have made on my mind.

Small animal patients that need general anesthesia may have preexisting cardiovascular diseases. To ensure oxygen delivery to the tissue, the cardiac output and oxygen content of the blood should be optimized. Cardiac output is the product of stroke volume and heart rate. Patients with cardiovascular diseases may have reduced cardiac output due to decreased stroke volume. The determinants of st...