Takotsubo cardiomyopathy is a form of transient, reversible left ventricular dysfunction that can mimic an acute coronary event. However, cardiac catheterization often reveals normal coronary arteries. Patients are often postmenopausal women who experience acute physical or emotional distress. The prognosis for this entity is quite favorable. In this report, we present three cases of Takotsubo ...

BACKGROUND Prolonged untreated acromegaly leads to a nonspecific myopathy characterized by ventricular dysfunction and failure. However, the mechanisms responsible for the alterations of cardiac pump function remain to be defined. Because cell death is implicated in most cardiac disease processes, the possibility has been raised that myocyte apoptosis may occur in the acromegalic heart, contrib...

background : the signal-averaged electrocardiography is a noninvasive method to evaluate the presence of the potentials generated by tissues activated later than their usual timing in the cardiac cycle. the purpose of this study was to demonstrate the correlation between the filtered qrs duration obtained via the signal-averaged electrocardiography and left ventricular dimensions and volumes an...

The autonomic nervous system interacts in the pathophysiology of heart failure. Dysfunction of the sympathetic nervous system has been identified as an important prognostic marker in patients with chronic heart failure. At present, cardiac sympathetic nerve imaging with 123-iodine metaiodobenzylguanidine [123-I MIBG] has been employed most frequently for the assessment of cardiac sympathetic in...

Thrombosis at the left ventricular outflow tract occurs without any detectable heart disease or predisposing factors only extremely rarely. A 48-year-old male visited Konkuk University Medical Center with loss of consciousness one month prior to presentation. Before he visited our hospital, he had been diagnosed with a cardiac tumor, which was located between the left atrium and posterior aorti...

background the early repolarization pattern (erp) has been considered a normal variant in electrocardiography (ecg) for a long time. nevertheless, increasing evidence has demonstrated its association with adverse outcomes. objectives the present study aimed to evaluate the prevalence of erp in the iranian general population and demonstrate its clinical and ecg correlates. methods a cross sectio...

OBJECTIVE To analyze left ventricle performance after myocardial revascularization associated to ventricular geometrics restoration by "pacopexy" in schemic myocardiopathy patients with significant ventricular dysfunction in whom ventricular restoration was obtained through special technique. METHODS Myocardial revascularization associated to ventricular geometrics restoration through special...

BACKGROUND Implantation of implantable cardioverter defibrillator for prevention of sudden cardiac death is deferred for 90 days after coronary revascularization, but mortality may be highest early after cardiac procedures in patients with ventricular dysfunction. We determined mortality risk in postrevascularization patients with left ventricular ejection fraction ≤35% and compared survival wi...

Functional mitral regurgitation is a highly prevalent condition among patients with ischemic and dilated cardiomyopathies. Arising from remodeling of both the mitral valve annulus and the left ventricle, it is associated with high mortality and morbidity. In selected patients, cardiac resynchronization therapy helps to reduce functional mitral regurgitation, but surgical intervention remains th...

Takotsubo cardiomyopathy or stress is a condition characterized by acute and transient left ventricular systolic dysfunction in the absence of coronary heart disease, occurring after an emotional physical stressful event. Cardiac these patients suspected to be secondary catecholamine induced cardiac myocyte injury via cyclic AMP-mediated calcium overload due endothelial dysfunction. Even though...