Background: Although the triggering role of both opium use and elevated plasma homocysteine level for progressing atherosclerosis and, therefore, appearing coronary heart disease has been clearly determined, no study are available with respect to the relation between these to risk profiles. In the present study and for the first time, we hypothesized that the opium addiction can be potentially ...

Predicting complications of diseases such as rheumatoid arthritis (RA) as well as the efficacy and toxicity of drugs used to treat the disease based on an understanding of genetic differences is leading to the development of highly individualized, personal medicine. The prevention of cardiovascular complications of RA has assumed greater importance as our ability to treat the underlying joint d...

Division of Translational Research and Clinical Epidemiology, Division of Cardiovascular Medicine, Wayne State University School of Medicine, Detroit, MI, USA; Cardiovascular Division, Brigham and Women’s Hospital, Boston, MA, USA; Department of Cardiology, Charite Universit€ats Medizin Berlin, Campus Benjamin Franklin, Berlin, Germany; Department of Cardiology, University Heart Center, Univers...

conclusions no significant variance was observed among patients underwent for cardiac catheterization, stemi, nstemi, unstable angina, and atrial fibrillation with respect to ft4, ft3, and tsh levels during coronary care unit hospitalization based on their profile data. results excluding those taking thyroid hormone preparations, 76.7% of patients admitted with acute coronary heart disease (st-...

Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine (E A Ashley MRCP, M T Wheeler MD), Department of Medicine (Prof R B Altman MD), Department of Bioengineering (Prof R B Altman), Division of Medical Genetics (Prof L Hudgins MD), Department of Pediatrics (A J Butte MD), and Department of Genetics (T E Klein PhD, K E Ormond MSc, Prof R B Altman), Stanford University ...

The significantly increased life expectancy of Western Society in the past several decades has been attributed to 2 major successes in the prevention and treatment of human disease: (1) the elimination of the scourge of common infectious diseases thanks to public health measures, vaccines, and antibiotic drug development and (2) the decline in cardiovascular morbidity and mortality because of t...