We report here the effect of diet and social environment on the carotid bifurcation atherosclerosis of 60 adult male cynomolgus monkeys (Macaca fascicularis) fed either an atherogenic diet (AD) or a more "prudent" diet (PD). Animals within each dietary condition lived either in unstable social groupings (which had their memberships reorganized on a regular basis) or in stable groupings. The exp...

Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region of bifurcation. Such morphological change in vessel largely affects parent as w...

A thorough understanding of the relationship between local hemodynamics and plaque progression has been hindered by an inability to prospectively monitor these factors in vivo in humans. In this study a novel approach for noninvasively reconstructing artery wall thickness and local hemodynamics at the human carotid bifurcation is presented. Three-dimensional (3D) models of the lumen and wall bo...

OBJECTIVE To investigate the atherosclerosis hypothesis in primary antiphospholipid syndrome (PAPS). METHODS The intima media thickness (IMT) of carotid arteries and other cardiovascular risk factors was measured in 20 patients with PAPS (mean (SD) age 35 (12) years) and in 20 controls matched for age and sex (34 (12) years). RESULTS The frequency of smoking, hypertension, and dyslipidaemia...

SUMMARY The purpose of this literature review is to disclose the relationship between the temporal profile of steno-occlusive changes in the cerebral arteries in moyamoya disease and the embryological evolution of the cerebral arteries. Steno-occlusive changes and progression occur in the sequence of embryological evolution of the primitive internal carotid artery in the early embryological sta...

Objective: To investigate the atherosclerosis hypothesis in primary antiphospholipid syndrome (PAPS). Methods: The intima media thickness (IMT) of carotid arteries and other cardiovascular risk factors was measured in 20 patients with PAPS (mean (SD) age 35 (12) years) and in 20 controls matched for age and sex (34 (12) years). Results: The frequency of smoking, hypertension, and dyslipidaemia ...

Duplex scanning of the carotid bifurcation has emerged as an accurate noninvasive means of predicting and quantifying carotid arterial stenoses. Compared with the more widely reported measurements of spectral broadening and peak frequency ratios, measurements of diastolic velocity ratios have theoretical advantages in predicting carotid artery stenosis. The use of diastolic velocity ratios betw...