Crimean-Congo hemorrhagic fever (CCHF) is a severe, often potentially fatal disease in humans, caused by infection with CCHF virus (CCHFV) belonging to the genus Nairovirus of the Bunyaviridae family. The current approach to treatment of CCHF is based on supporting hematologic and coagulation status of the patient, with replacement of cells and factors as needed, but use of ribavirin is controv...

background: the world health organization (who) declares crimean congo hemorrhagic fe­ver (cchf) endemic in turkey. despite the magnitude of problem, no documented evi­dence exists in turkey, which reveals the aware­ness and practices of the country's adult popula­tion regarding cchf, its spread, symptoms, treatment, and preven­tion. this study was conducted to assess the level of knowledge, at...

Background: Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal tick-borne viral disease. Hard ticks are both carriers and reservoirs of the CCHF virus. In this regard, the present study is aimed to investigate the CCHF virus infection in collected ticks from livestock in Gonabad City (southwest of Razavi Khorasan province) in eastern Iran. Methods: This descriptive study was perfo...

This refers toDr. Levent Doganci’s letter published in your valuable Journal about Congo Hemorrhagic Fever (CCHF) entitled “Crimean Congo Haemorrhagic Fever as an indication for use of Ribavirin”.1 CrimeanCongo Hemorrhagic Fever is a widely distributed lethal disease, worldwide.2 Human are usually infected with CCHF virus through a tick bite or close contact with viral contaminated tissues or w...

Aim: The urokinase-type plasminogen activator (uPA) system consists of a protease, receptor (urokinase-type receptor, uPAR), and inhibitors that can be expressed on various cell types. Previous literature shows the amount soluble (suPAR) secreted from affected cells is higher in Crimean-Congo hemorrhagic fever (CCHF) patients than healthy controls. Thus, we aimed to investigate diagnostic value...

BackgroundCrimean-Congo Hemorrhagic Fever (CCHF) is a particular regional concern because of endemicity in Afghanistan and many neighboring countries. The prevalence CCHF has been increasing this region. These concerns are compounded there no vaccine or therapeutic for lacks adequate public health infrastructure preventing, detecting, containing cases. This investigation aimed to study the epid...

conclusions the present study showed that cchf is highly prevalent in high risk occupational groups in zahedan, iran. further surveillance, teaching and prevention programs are recommended. results out of 362 patients with cchf (86% male, 14% female; with age range 12-78 years), 123 (34%) were slaughterhouse workers, 103 (28.5%) livestock handlers and farmers, 32 (9%) housewives, 7 (2%) student...

Tick-borne diseases pose a serious threat to human health in South-Eastern Europe, including Kosovo. While Crimean-Congo hemorrhagic fever (CCHF) is a well-known emerging infection in this area, there are no accurate data on Lyme borreliosis and tick-borne encephalitis (TBE). Therefore, we sampled and tested 795 ticks. Ixodes ricinus (n = 218), Dermacentor marginatus (n = 98), and Haemaphysalis...