نتایج جستجو برای: ccl22

تعداد نتایج: 1448  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2012
Lynda J Hatam James A Devoti David W Rosenthal Fung Lam Allan L Abramson Bettie M Steinberg Vincent R Bonagura

PURPOSE Respiratory papillomas, caused by human papillomaviruses types 6 and 11 (HPV6/11), are premalignant lesions with potential for malignant conversion. The cytokine and chemokine micromilieu of papillomas is T(H)2-like with a marked absence of IFN-γ expression. To illuminate why patients with recurrent respiratory papillomatosis (RRP) fail to effectively control their disease, we further i...

Journal: :Molecular cancer therapeutics 2012
De-Kuan Chang Jianhua Sui Shusheng Geng Asli Muvaffak Mei Bai Robert C Fuhlbrigge Agnes Lo Anuradha Yammanuru Luke Hubbard Jared Sheehan James J Campbell Quan Zhu Thomas S Kupper Wayne A Marasco

Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of neoplastic disorders characterized by clonally derived and skin-homing malignant T cells that express high level of chemokine receptor CCR4, which is associated with their skin-homing capacity. CCR4 is also highly expressed on T-regulatory cells (Tregs) that can migrate to several different types of chemotactic ligand CCL17- and CCL22...

Journal: :Cancer research 2009
Michael Gobert Isabelle Treilleux Nathalie Bendriss-Vermare Thomas Bachelot Sophie Goddard-Leon Vanessa Arfi Cathy Biota Anne Claire Doffin Isabelle Durand Daniel Olive Solène Perez Nicolas Pasqual Christelle Faure Isabelle Ray-Coquard Alain Puisieux Christophe Caux Jean-Yves Blay Christine Ménétrier-Caux

Immunohistochemical analysis of FOXP3 in primary breast tumors showed that a high number of tumor-infiltrating regulatory T cells (Ti-Treg) within lymphoid infiltrates surrounding the tumor was predictive of relapse and death, in contrast to those present within the tumor bed. Ex vivo analysis showed that these tumor-infiltrating FOXP3(+) T cells are typical Treg based on their CD4(+)CD25(high)...

2017
Ting Yang Yan Li Zhe Lyu Kewu Huang Chris J Corrigan Sun Ying Wei Wang Chen Wang

BACKGROUND Increased proinflammatory cytokines and chemokines might contribute to infiltration of inflammatory cells and remodeling in airways of asthma. Although these molecules may be associated with asthma, there is lack of systemic evidence showing which and how important these events are in the disease. We aimed to analyze the concentrations of these molecules in the airways and relationsh...

Journal: :Journal of immunology 2005
Hormas Ghadially Xiao-Lan Ross Claudia Kerst Jun Dong Angelika B Reske-Kunz Ralf Ross

The activated T cell-attracting CC chemokine CCL22 is expressed by stimulated B cells and mature dendritic cells (DC). We have cloned and sequenced the complete mouse gene, including 4 kb of the 5'-flanking promoter region, and detected two distinct sites for initiation of transcription by 5'-RACE. Reporter gene assays indicate that the promoter reflects the specificity of the endogenous gene. ...

Journal: :American Journal of Physiology-Lung Cellular and Molecular Physiology 2020

Journal: :Journal of immunology 1998
D P Andrew M S Chang J McNinch S T Wathen M Rihanek J Tseng J P Spellberg C G Elias

STCP-1 stimulated T cell chemoattractant protein-1 (STCP-1) (macrophage-derived chemokine; MDC), a recently described CC chemokine for chronically activated T lymphocytes, was found to act specifically on a subset of memory CD4 lymphocytes that displayed a Th2 cytokine profile. Also, STCP-1, thymus and activation regulated chemokine (TARC), eotaxin, and eotaxin-2 acted specifically on in vitro ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید