BACKGROUND Several studies have shown an elevated prevalence of coeliac disease (CD) in sibs of coeliac patients (risk 8-12%). AIM AND METHOD We evaluated the risk that sibs of children with CD will also develop CD. This cohort of 188 Italian families was composed of probands with CD, at least one sib and both parents. CD status was determined and human leucocyte antigen (HLA)-DQ genotyping p...

Cathepsins are lysosomal cysteine proteases, which are involved in a variety of physiologic processes such as proenzyme activation, antigen presentation, tissue remodeling, bone matrix resorption, and pathologic processes such as facilitating tumor invasion and modulating the process of programmed cell death. This study aimed to evaluate the pattern of cathepsin D (CD) expression in chronic pla...

Adres do korespondencji: dr n. med. Aneta I. Gziut, Klinika Kardiologii Inwazyjnej, Centralny Szpital Kliniczny MSWiA, ul. Wołoska 137, 02-507 Warszawa, tel.: +48 22 508 11 00, faks: +48 22 508 11 77, e-mail: [email protected] Przedstawiamy przypadek 46-letniej chorej przekazanej ze szpitala rejonowego w ramach ostrego dyżuru hemodynamicznego ze wstępnym rozpoznaniem ostrego zes...

BACKGROUND No data are available on HIV/hepatitis B virus (HBV) or hepatitis C virus coinfection in Togo, and patients are not routinely tested for HBV infection. OBJECTIVE To determine the prevalence of HBV and the risk of HBV drug resistance during antiretroviral treatment in HIV-coinfected patients in Togo. METHOD  This cross-sectional study was carried out in Lomé, Togo, from January 20...

GOALS AND BACKGROUND Inflammatory bowel disease (IBD) serology testing is often used in patients with indeterminate colitis (IC) to help distinguish between ulcerative colitis (UC) and Crohn's disease (CD). We investigated the performance of serology testing in predicting future diagnosis in this setting. STUDY This was an observational study of individuals with IC at a single center who unde...

Purpose Primary malignant solitary fibrous tumor (SFT) of the orbit is a rare spindle cell neoplasm that requires excisional biopsy for histopathological diagnosis. We present a clinical case using contemporary immunohistochemical stains, report on the latest World Health Organization classification, and provide a review of the literature. Observations Report of a single case of a 65 year old...

BACKGROUND AND PURPOSE Hemifacial spasm (HFS) is a common movement disorder, but its prevalence in different populations has not been elucidated. METHODS We reviewed all patients with HFS currently followed at the Baylor College of Medicine Movement Disorders Clinic and compared their demographic and clinical data with a control group of patients with cranial-cervical dystonia (CD). RESULTS...

AIM To evaluate the short health scale (SHS), a new, simple, four-part visual analogue scale questionnaire that is designed to assess the impact of inflammatory bowel disease (IBD) on health-related quality of life (HRQOL), in Korean-speaking patients with IBD. METHODS The SHS was completed by 256 patients with Crohn's disease (CD) and ulcerative colitis (UC). Individual SHS items were correl...