نتایج جستجو برای: cd146

تعداد نتایج: 620  

Journal: :Human molecular genetics 2012
Ariya D Lapan Anete Rozkalne Emanuela Gussoni

Muscle side population (SP) cells are rare myogenic progenitors distinct from satellite cells, the known tissue-specific stem cells of skeletal muscle. Studies in mice demonstrated that muscle SP cells give rise to satellite cells in vivo. Given that muscle SP cells are heterogeneous, it has been difficult to prospectively enrich for myogenic progenitors within the SP fraction, particularly fro...

Journal: :American Journal of Physiology-Cell Physiology 2019

2012
Aaron W. James Janette N. Zara Mirko Corselli Michael Chiang Wei Yuan Virginia Nguyen Asal Askarinam Raghav Goyal Ronald K. Siu Victoria Scott Min Lee Kang Ting Bruno Péault Chia Soo

Human perivascular stem cells (PSCs) can be isolated in sufficient numbers from multiple tissues for purposes of skeletal tissue engineering. PSCs are a FACS-sorted population of 'pericytes' (CD146+CD34-CD45-) and 'adventitial cells' (CD146-CD34+CD45-), each of which we have previously reported to have properties of mesenchymal stem cells. PSCs, like MSCs, are able to undergo osteogenic differe...

Journal: :Neuroscience 2013
H Duan Y Luo H Hao L Feng Y Zhang D Lu S Xing J Feng D Yang L Song X Yan

The soluble form of CD146 has been reported to be present in various inflammatory diseases and displays pro-inflammatory properties. However, little is known about sCD146 in multiple sclerosis (MS). Here we show that sCD146 is significantly elevated in the cerebrospinal fluid of patients with active MS compared with that of inactive MS or patients with non-demyelinating diseases. Moreover, abno...

2017
Tiziana Persichini Alessia Funari Marco Colasanti Benedetto Sacchetti

Recent observation identifies subendothelial (mural) cells expressing MCAM, a specific system of clonogenic, self-renewing, osteoprogenitors (a.k.a, "mesenchymal stem cells") in the microvascular compartment of post-natal human bone marrow (BM). In this study, we used MCAM/CD146, as a marker to localize, isolate and assay subendothelial clonogenic cells from the microvasculature of postnatal hu...

2016
Mehri Fayazi Mojdeh Salehnia Saeideh Ziaei

BACKGROUND The aim of this study was to investigate the percentage of the stem cells population in human endometrial tissue sections and cultured cells at fourth passage. METHODS Human endometrial specimens were divided into two parts, one part for morphological studies and the other part for in vitro culture. Full thickness of human normal endometrial sections and cultured endometrial cells ...

2017
Fei Huang Jie Ding Li Miao Yingxuan Zhao Mingye Zhang Caiyun Chen Gaoyi Wu Songshan Lin Feng Wang

Objective: Inhibition of IL-17 on periodontal ligament stem cells (PDLSCs) proliferation osteogenic differentiation had been reported. This study was to investigate the effect of IL-17 on human PDLSCs (hPDLSCs). Methods: Isolated hPDLSCs from healthy fresh premolars were identified and then transfected with IL-17 silencing lentivirus plasmid. Then cell proliferation, colony formation, apoptosis...

2014
Markus Loibl Andreas Binder Marietta Herrmann Fabian Duttenhoefer R Geoff Richards Michael Nerlich Mauro Alini Sophie Verrier

Tissue engineering techniques for the regeneration of large bone defects require sufficient vascularisation of the applied constructs to ensure a sufficient supply of oxygen and nutrients. In our previous work, prevascularised 3D scaffolds have been successfully established by coculture of bone marrow derived stem cells (MSCs) and endothelial progenitor cells (EPCs). We identified stabilising p...

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