In this paper, we consider the identification problem arising in the ageperiod-cohort models, as well as in the extended chain ladder model. We propose a canonical parametrization based on the accelerations of the trends in the three factors. This parametrization is exactly identified. It eases interpretation, estimation and forecasting. The canonical parametrization is shown to apply for a cla...

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This study was conducted to determine whether multivalent, precipitating antigens are required for formation of subepithelial electron-dense immune deposits in glomeruli. 2-nitro-4-azidophenyl (NAP) was conjugated with variable density to human serum albumin (HSA) to yield nonprecipitating (NAP3.1 X HSA and NAP11.4 X HSA) and precipitating (NAP19.7 X HSA) antigens with antibodies to the hapten....

The identification of the base substitution responsible for Ag(x/y) completes the description of the antigen group polymorphisms associated with the apolipoprotein B polypeptide. Surprisingly, all five antigen group polymorphisms alter restriction endonuclease cleavage sites and have associated restriction fragment length polymorphisms, thereby providing a convenient alternative for antigen gro...

Safety and antigenicity of a purified preparation of Salmonella typhosa Vi antigen was evaluated in human volunteers. Dosages of Vi antigen at 25, 50, and 100 mug were less toxic than U.S. standard typhoid vaccine (lot 6A) containing 5 X 10(8) bacteria per dosage. Vi antigen in comparison with the standard typhoid vaccine induced higher hemagglutinating antibody but lower bactericidal antibody ...

To better appreciate mortality differences between two countries, it is useful to compare sex-specific rates across both age groups and time. Lexis diagrams facilitate this,1 but have remained underutilized. Combining two Lexis diagrams allows us to effectively visualize changes in comparative mortality ratios between two countries over time, between years, and within cohorts. To highlight this...

The author reviews Mirosław Jankowiak’s study Lexicon of Belarusian Dialects in Lithuania. Linguistic Heritage the Baltic-Slavic Borderland (Prague 2022). In her opinion, it is a cognitively valuable dialect vocabulary beyond borders Belarus. Set methodologically area several linguistic sub-disciplines – dialectology, sociolinguistics, geography, lexicography presents comprehensive description ...

Usual transformations of the current lexis and its stock, semantics as well treatments particular words reflect some shifts in social consciousness. They are provoked by changes political, cultural, psychological spheres life. The author this article aim at analysis factors which facilitate such lexical units semantic axiological characteristics modern discourse. Among tasks is considered a dif...