Some 10 years ago, it was proposed that different quantities, including time, space or number, are processed by a common mechanism (Walsh, 2003; Pinel et al., 2004; Cohen Kadosh et al., 2005), henceforth called generalized magnitude system (GMS). This presented an important attempt at theoretically integrating data across various literatures, and became very influential (e.g., Burr et al., 2010...

Oval cell proliferation precedes neoplasia in many rodent models of hepatocellular carcinoma and prevention of this proliferative response can reduce the risk of subsequent carcinoma. This study aimed to determine whether a selective cyclo-oxygenase-2 (COX-2) inhibitor, SC-236, affects (i) the oval cell response to liver injury in a mouse model of hepatocarcinogenesis and (ii) an oval cell line...

BubR1 is a key protein mediating spindle checkpoint activation. Loss of this checkpoint control results in chromosomal instability and aneuploidy. The transcriptional regulation of the cell cycle regulated human BUB1B gene, which encodes BubR1, was investigated in this report. A minimal BUB1B gene promoter containing 464 bp upstream from the translation initiation codon was sufficient for cell ...

BACKGROUND To find the maximum tolerated dose for ifosfamide in combination with paclitaxel and carboplatin in small-cell lung cancer patients (SCLC), who are resistant to cyclophosphamide, doxorubicin and etoposide (CDE). PATIENTS AND METHODS Different dose schedules of ifosfamide were combined with fixed doses of paclitaxel 175 mg/m2 and carboplatin AUC 6 mg/ml min. Included were 30 patient...

Twenty children with various diaphragmatic anomalies, managed over a period of 3 years, are presented. These included congenital diaphragmatic hemia (CDH 10), congenital eventration of diaphragm (CDE 6) and hiatus hernia with gastro-esophageal reflux (HH-GER 4). Clinical presentation of these children was: respiratory distress (7), recurrent respiratory tract infcction \\1' failure to thrive (I...

Abstract In recent years, the BIM method has been increasingly used in pilot projects for planning and realization of road construction projects. Due to strong political demand expand applications fields BIM, there is also an increasing a common data environment (CDE), as central component successful consistent application [1]. this context, uniform requirements, which currently exist only limi...

Grape stalk wastes generated in the wine production process were used for the removal of cadmium and lead ions from aqueous solutions. The experimental breakthrough curves (BTC) were obtained from fixedbed columns. Experiments were carried out to evaluate the influence of both inlet metal concentration and sorbent particle size. The experimental data were fitted to the Thomas model, a well-esta...

Human object extraction from infrared image has broad applications, and has become an active research area in image processing community. Combined with chaos differential evolution (CDE) algorithm and morphological operators, a novel infrared human target extraction method is proposed based on nonextensive fuzzy entropy. Firstly, the image was transformed into a fuzzy domain by fuzzy membership...

In the present article we propose two novel variants of Differential Evolution (DE) namely Centroid Differential Evolution (CDE) and Differential Evolution with local Search (DELS) for solving unconstrained, single objective, optimization problems. Both the algorithms make use of geometric centroid to enhance the performance of basic DE in terms of average fitness function value as well as in t...