Purpose Approximately 10 million U.S. adults suffer from chronic daily headache (CDH), resulting in major disability and impaired quality of life. Recent evidence suggests that the cause of pain may be related to inflammation. Dietary interventions that reduce the inflammatory response could help eliminate the development of pain in chronic pain syndromes such as CDH. The goal of this pilot stu...

During the past 10 years, significant changes have occurred in the diagnosis and management of congenital diaphragmatic hernia (CDH). The unsuspected birth of an infant who has CDH, the emergency transfer to a center where a pediatric surgeon and neonatologist are available, and the rush to the operating room for repair are a memory. Today we frequently provide prenatal counseling to parents of...

OBJECTIVE To analyze the prevalence and demography of chronic daily headache (CDH) with analgesic overuse. METHODS A population of 9,984 inhabitants aged 14 or older living in Santoña, Spain, was studied. The authors personally interviewed 4,855 subjects, using a quota sampling approach. Those with headache for > or = 10 days/month and some analgesic use were asked to fill in a diary over the...

A variety of medications and treatment interventions, including antiepileptic drugs, tricyclic antidepressants, selective serotonin reuptake inhibitors, combined serotonin and norepinephrine reuptake inhibitors, β blockers, calcium channel antagonists, α2-adrenergic agonists, nonsteroidal anti-inflammatory drugs, muscle relaxants, occipital nerve blocks, and botulinum toxin type A injections, h...

UNLABELLED There are controversial associations between headaches and psychological symptoms. OBJECTIVE To design a profile of neuroticism, a term that groups variables related to negative personality traits, in patients with chronic daily headache (CDH) when compared to episodic migraine (EM) patients, applying the Factorial Scale of Emotional Adjustment/Neuroticism (NFS). METHOD One hundr...

Despite advances in neonatal care including prenatal diagnosis, conventional ventilation, surfactant, high frequency oscillation, nitric oxide and extracorporeal membrane oxygenation (ECMO) the diagnosis of CDH is reported to carry a high mortality rate. Pulmonary hypoplasia and persistent pulmonary hypertension are major factors that contribute to death. In an effort to improve the survival of...

Several genes that encode members of the cadherin superfamily have been identified in Caenorhabditis elegans. Based on the roles of cadherins in vertebrates and Drosophila, it is expected that they function in the control of epithelial morphogenesis, an event which is poorly understood at the molecular level in C. elegans. Reporter genes under the control of upstream sequences from one of these...

In 2010, the congenital diaphragmatic hernia (CDH) EURO Consortium published a standardized neonatal treatment protocol. Five years later, the number of participating centers has been raised from 13 to 22. In this article the relevant literature is updated, and consensus has been reached between the members of the CDH EURO Consortium. Key updated recommendations are: (1) planned delivery after ...

An anterior congenital diaphragmatic hernia (CDH) is a diaphragmatic defect that allows the passage of abdominal organs into the thorax. It is typically asymptomatic (the diagnosis is incidental) and it requires surgical correction. In this paper we present a 6 year-old girl affected by spinal muscular atrophy (SMA) who was diagnosed with anterior CDH. Four years after laparoscopic closure of t...

BACKGROUND The ability of fungal cellobiose dehydrogenase (CDH) to generate H2O2 in-situ is highly interesting for biotechnological applications like cotton bleaching, laundry detergents or antimicrobial functionalization of medical devices. CDH's ability to directly use polysaccharide derived mono- and oligosaccharides as substrates is a considerable advantage compared to other oxidases such a...