The activity of human replication protein A (RPA) in DNA replication and repair is regulated by phosphorylation of the middle RPA2 subunit. It has previously been shown that up to nine different N-terminal residues are modified in vivo and in response to genotoxic stress. Using a novel antibody against phospho-Ser(29), a moiety formed by cyclin-Cdk, we observed that RPA2 was phosphorylated duri...

rinbow trout (oncorhynchus mykiss) is an important fish species in aquaculture. the bacterial disease caused the decline in the production of this fish. lactococcus garvieae is one of the most serious infectious agents that caused disease with economical losses in fish farms. streptococosis have signs similar to lactococcosis. therefore the definite diagnosis is sometimes complicated. in the la...

Background: The expression of bio-therapeutic proteins in mammalian cells, such as CHO, attains high homogeneity related to post-translational modifications. Although CHO remains the most popular cell line for bestselling biotherapeutic proteins on the market, there are still drawbacks such as expensive culture media, long time line, and high drug cost. Recently, researches on a novel Leishmani...

in this research, the effects of thidiazuron pulse treatment and salicylic acid were examined to improve vase life and maintain the quality of alstroemeria ҅modena҆ cut flowers. the experiment was done in a factorial experiment based on rcd with 16 treatments, 3 replications and 48 plots. the flowers were placed in different concentrations of thidiazuron (0, 10, 20, and 50 μm) and salicylic acid ...

Background: Nitric Oxide (NO) is a very important signaling molecule which acts as regulator of many physiological processes in tissues including epithelial cell gastrointestinal tract. In this study we investigated the effects L-Arginine NO progenitor and L-NAME inhibitor on number height Jejunum female rats.

AMA Alvarez-Coronel L, Rivera-Moncada Saul Lino-Silva L. Prognostic significance of tumour budding in Merkel cell carcinoma. Polish Journal Pathology. 2023. doi:10.5114/pjp.2023.129404. APA Alvarez-Coronel, L., Rivera-Moncada, & Lino-Silva, (2023). https://doi.org/10.5114/pjp.2023.129404 Chicago Leslye A, Luisa F and Leonardo Lino-Silva. "Prognostic carcinoma". Harvard MLA A et al. carcinoma." ...

in the present study, streptomyces gulbargensis and its mutant form, s.gulbargensis mu24, immobilized on polyurethane foam were investigated for the production of l-asparaginase using groundnut cake extract as medium. the medium with an initial ph of 8.5 was inoculated with free and immobilized cells separately and then subjected to fermentation by incubation at 40oc and shaking at 200 rev/min....

Abstract Flotation performance is influenced by many hydrodynamic variables, such as impeller speed, airflow rate, and cell geometry. These variables’ effects interactions remain unsatisfactorily explored, especially concerning scaling-up procedures. As an innovative approach, this study considered factorial-designed experiments to explore the of factors (impeller tip speed superficial gas velo...