نتایج جستجو برای: cellular and humoral immunity
تعداد نتایج: 16867940 فیلتر نتایج به سال:
mTOR has important roles in regulation of both innate and adaptive immunity, but whether and how mTOR modulates humoral immune responses have yet to be fully understood. To address this issue, we examined the effects of rapamycin, a specific inhibitor of mTOR, on B cell and CD4 T cell responses during acute infection with lymphocytic choriomeningitis virus. Rapamycin treatment resulted in suppr...
Features of Cellular and Humoral Immunity Functioning in Patients with Juvenile Rheumatoid Arthritis
Although the initial isolates of the severe acute respiratory syndrome (SARS) coronavirus (CoV) are sensitive to neutralization by antibodies through their spike (S) glycoprotein, variants of S have since been identified that are resistant to such inhibition. Optimal vaccine strategies would therefore make use of additional determinants of immune recognition, either through cellular or expanded...
A major challenge in combating the human immunodeficiency virus (HIV) epidemic is the development of vaccines capable of inducing potent, persistent cellular immunity and broadly reactive neutralizing antibody responses to HIV type 1 (HIV-1). We report here the results of a preclinical trial using the chimpanzee model to investigate a combination vaccine strategy involving sequential priming im...
HIV serodiscordant couples are an extremely useful tool for examining immune responses that may contribute to reduced transmission or protection from HIV infection. A homozygous 32-base pair deletion in the gene encoding the Chemokine receptor 5 protein (CCR5) is strongly associated with protection from HIV infection (Huang et al., 1996). In contrast, the contribution of humoral, cellular and i...
BACKGROUND Previous study shows that cellular immunity and family relationships are each correlated with the severity of depression and suggests that the psycho-immunological theory should look at the relation between immunity and family life. The aim of the present study based on the same sample is to investigate if similar correlations exist with humoral immunity. SUBJECTS AND METHOD 498 in...
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