The authors would like to make the following correction to the above mentioned article. The title should be changed from ‘‘OnabotulinumtoxinA is Effective in Patients with Urinary Incontinence due to Neurogenic Detrusor Activity Regardless of Concomitant Anticholinergic Use or Neurologic Etiology’’ to ‘‘OnabotulinumtoxinA is Effective in Patients with Urinary Incontinence due to Neurogenic Detr...

BACKGROUND People with dementia may be particularly sensitive to cognitive impairment induced by anticholinergic and sedative medicines. OBJECTIVE This study aimed to examine if utilisation of medicines with anticholinergic and sedative effects changed before and after initiation of anti-dementia therapy. METHODS A retrospective cohort study was conducted using Australian pharmacy claim dat...

AIMS To determine if the outcomes of intradetrusor botulinum toxin A (BTX-A) injections for the management of refractory overactive bladder (OAB) symptoms are different if performed due to lack of anticholinergic efficacy versus medication intolerability. METHODS Retrospective chart review was performed on all patients undergoing intradetrusor BTX-A (BOTOX®, Allergan Inc., Irvine, CA) injecti...

Definitive risk factors for constipation in palliative care remain poorly defined. A retrospective analysis of 211 admissions to a palliative care unit was undertaken, with the main aim being to identify some factors, which influence laxative prescription. On univariate analysis, significant unadjusted associations were found between two or more prescribed laxatives and a diagnosis of malignanc...

Datura Stramonium (DS) is a in our country; it grows wild rural areas without the need for agriculture. DS can also be used as herbal medicine respiratory system diseases such asthma and bronchitis, hemorrhoids dermatological eczema. It may lead to anticholinergic symptoms mydriasis, tachycardia, dry skin, flushing urinary retention humans due its atropine content, when affects central nervous ...

This report aims at raising clinical awareness for the diagnosis of atypical presentations of neuroleptic malignant syndrome (NMS). We describe the case of a female patient with NMS symptoms, except fever, after starting the use of chlorpromazine. The afebrile condition delayed the consideration of NMS by the emergency clinicians who provided her initial assessment. Before this consideration, a...

OBJECTIVES To investigate whether solifenacin intervention leads to any changes in bowel symptoms, and the types of impacts imposed on bowel symptoms in patients with overactive bladder (OAB). METHODS This prospective, single-arm observational study included 40 adult patients who underwent anticholinergic treatment for OAB. Outcome measures were determined by examining differences in voiding ...

Increasing suppression of gastric secretion by anticholinergic drugs is accompanied by a rising mucus concentration; the actual output of mucus shows little change despite a marked reduction in the secretory volume. The problems involved in the estimation of mucus secretion and the importance of the above findings in relation to the therapeutic use of anticholinergic drugs in peptic ulceration ...

BACKGROUND Anticholinergic properties of certain medications often go unrecognized, and are frequently used by the elderly population. Few studies have yet defined the long-term impact of these medications on the incidence of cognitive impairment. METHODS We report a 6-year longitudinal, observational study, evaluating 1,652 community-dwelling African American subjects over the age of 70 year...