Cardiopulmonary resuscitation (CPR) may be followed by slow recovery of brain function. The possible role of bicarbonate therapy was assessed by analysis of arterial blood and cerebrospinal fluid (CSF) in 20 dogs during cardiac arrest and CPR. Samples were taken in the control period and every 5 minutes postarrest for 20 minutes. Group I received no post-arrest CPR. Arterial pH fell from 7.37 t...

The 49 Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida was held in Barcelona, Spain, from 29 June to 2 July 2005. We are especially grateful to Amparo Cuxart and Esther Pages who, together with their team, made us all very welcome. The city of Barcelona has much to offer, from the medieval elegance of the Gothic Quarter, to the rather more idiosyncratic architectu...

Thirty four infants were studied; 21 with acute gastroenteritis, dehydration, and metabolic acidosis and 13 who served as controls. All infants with metabolic acidosis and without neurological signs had a normal to near normal cerebrospinal fluid acid base balance, but five with metabolic acidosis and severe neurological signs had cerebrospinal fluid acid base disequilibrium. Acute metabolic ac...

Cerebrospinal fluid imaging plays a significant role in the clinical diagnosis of brain disorders, such as hydrocephalus and Alzheimer's disease. While three-dimensional images of cerebrospinal fluid are very detailed, the complex structures they contain can be time-consuming and laborious to interpret. This paper presents a simple technique that represents the intracranial cerebrospinal fluid ...

Sinclair and Hinshaw (1951) reported that ischaemic tingling was diminished or absent in patients with spinal or cerebral lesions causing defective tactile sensibility, and suggested that " It may even be that a diminution in the sensation of tingling affords a more sensitive test for such defects than standard testing methods ". However, the present work suggests that the relation between ting...

De novo synthesis in the central nervous system of IgG antibodies to human T cell lymphotropic virus type III (HTLVHI) (lymphadenopathy associated virus) was shown in seven of 10 seropositive men who had syphilis but not the acquired immune deficiency syndrome (AIDS) or AIDS related complex. None of these men showed neurological symptoms when the serum and cerebrospinal fluid were collected. Pl...

The 50 Annual Scientific Meeting of the Society for Research into Hydrocephalus and Spina Bifida took place in the historic surroundings of Queens’ College in Cambridge, England. Delegates were warmly welcomed by Professor John Pickard and his organising team from the Department of Academic Neurosurgery, and we are especially indebted to Dr. Hugh Richards for his tireless work to make this conf...

The 52 Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida was held at Brown University in Providence, Rhode Island at the invitation of Drs John Duncan, Conrad Johanson and Gerald Silverberg. The Society would like to thank the organizers, especially Conrad and his wife, Nancy, for making the meeting such a success. Brown University was founded in 1764, one of the ei...

dear editor: we would like to present a modified method for cerebrospinal fluid collection in anesthetized rat. this method is easy and applicable in many laboratories interested by research on cellular and molecular effects of csf on different pathways.

This study of the effects of certain drugs, gas mixtures, and other stimuli on the cerebrospinal fluid pressure corroborates previous conclusions that alterations in cerebral blood flow are reflected by similar changes in the cerebrospinal fluid pressure in the same direction. The hypothesis is advanced that the elevations and depressions in cerebrospinal fluid pressure resulting from these age...