The purpose of this study was to determine whether sectioning the cervical septum is associated with intraoperative bleeding, incompetent cervix, and secondary infertility. In this prospective observational study, fourteen women with complete septate uterus who had a history of repeated pregnancy loss and infertility were treated hysteroscopically. Preoperative history included 35 pregnanci...

BACKGROUND Congenital uterine malformations are the result of disturbances in mullerian duct development. In patients with recurrent miscarriage, the reported frequency of uterine anomalies varies widely, from 1.8% to 37.6%. There are reports in which cervical cerclage has been shown to prevent preterm labor in uterine anomalies. The aim of this study was to compare the role of cervical cerclag...

The objective of this study is to describe the clinical outcomes of patients treated for cervical pregnancy with or without methotrexate (MTX) and to evaluate the effects of MTX in the treatment of cervical pregnancy. Between January 1993 and February 2000, 31 patients were diagnosed with cervical pregnancy. Twenty-two patients were treated with MTX chemotherapy and nine patients were treated w...

OBJECTIVE To compare the incidences of preterm delivery, cervical incompetence treated by cerclage, placental implantation or retention problems (ie, placenta praevia, placental abruption and retained placenta) and postpartum haemorrhage between women with and without a history of pregnancy termination. DESIGN  A retrospective cohort study using aggregated data from a national perinatal regis...

OBJECTIVE To determine what constitutes normal cervical changes during the second half of pregnancy in parous women delivering at term. DESIGN The study comprises 21 healthy, pregnant parous women who all gave birth at term. They were examined with transvaginal ultrasound every two weeks from 24 gestational weeks until delivery. Cervical length and width were measured. The inner cervical os w...

In primate pregnancy, circulating relaxin, solely a product of the corpus luteum, peaks in the first trimester of pregnancy then declines and levels off for the remainder of pregnancy. Relaxin actions in pregnancy include increasing cervical pro-MMP-1 and pro-MMP-3 and decreasing TIMP-1, changes which soften the cervix. Relaxin, from early pregnancy, increases endometrial natural killer cells, ...

AIM Feasibility and reliability of tissue Doppler imaging-(TDI-) based elastography for cervical quantitative stiffness assessment during all three trimesters of pregnancy were evaluated. MATERIALS AND METHODS Prospective case-control study including seventy-four patients collected between the 12th and 42nd weeks of gestation. The tissue strain (TS) was measured by two independent operators a...

Results A 21 year old primigravid woman admitted to our clinic with suspicion of cervical incompetence at 22 weeks of gestation. She complained of light vaginal bleeding and a vaginal mass. She did not have any pain. Her past medical history was uneventful. A detailed abdominal 2D ultrasound scan was performed to verify the presence of the pregnancy and research for associated anomalies. The US...

Preterm labour and resultant preterm birth are the most important problems in perinatology. Countless efforts have failed to establish a single effective treatment of preterm labour, partly because the mechanisms regulating the uterus and cervix during pregnancy are not well understood. New knowledge is needed to inhibit early progression of labour (uterine contractility and cervical ripening),...