Comparative genome hybridization (CGH) is a laboratory method to measure gains and losses of chromosomal regions in tumor cells. It is believed that DNA gains and losses in tumor cells do not occur entirely at random, but partly through some flow of causality. Models that relate tumor progression to the occurrence of DNA gains and losses could be very useful in hunting cancer genes and in cance...

Synthesizing computer-generated holograms (CGHs) of a general three-dimensional (3D) object is usually a heavy computational task. We propose and demonstrate a new algorithm for computing CGHs of 3D objects. In our scheme, many different angular projections of computer-designed 3D objects are numerically processed to yield a single two-dimensional complex matrix. This matrix is equivalent to th...

Cervicogenic headache (CGH) is a relatively common form of headache stemming from the neck structures which presents some pathophysiological condition probably linked together with various pain-producing factors. This report presents a series of 9 patients suffering from cervicogenic headache and the results achieved by means of epidural steroid (methylprednisolone 40 mg) injection into the epi...

Array comparative genomic hybridization (cgh) is a microarray technology for measuring the relative copy number of thousands of genomic regions. Visual examination of cgh profiles shows that genomic changes occur on a variety of length scales. Such changes may be characteristic of phenotypic variables such as tumor type and gene mutational status. To aid in identifying such features and explori...

Array based comparative genomic hybridization (array-CGH) has merged as a highly efficient technique for the detection of chromosomal imbalances. Characteristics of these DNA copy number aberrations provide the insights into cancer, and they are useful for the diagnostic and therapy strategies. In this paper, we propose a statistical bivariate model for array CGH data in the stationary wavelet ...

One common way to measure asphere and freeform surfaces is the interferometric Null test, where a computer generated hologram (CGH) is placed in the object path of the interferometer. If undetected phase errors are present in the CGH, the measurement will show systematic errors. Therefore the absolute phase of this element has to be known. This phase is often calculated using scalar diffraction...

MOTIVATION Genome analysis has become one of the most important tools for understanding the complex process of cancerogenesis. With increasing resolution of CGH arrays, the demand for computationally efficient algorithms arises, which are effective in the detection of aberrations even in very noisy data. RESULTS We developed a rather simple, non-parametric technique of high computational effi...

Comparative genomic hybridization (CGH) is an indirect DNA-based test which allows for the accurate analysis of aneuploidy involving any of the 24 types of chromosomes present (22 autosomes and the X and Y sex chromosomes). Traditionally, embryos have been screened using fluorescence in situ hybridization (FISH)--a technique that was limited in the number of chromosomes able to be identified in...

There is growing evidence that gene amplifications were present in neural stem and progenitor cells during differentiation. We used array-CGH to discover copy number changes including gene amplifications and deletions during differentiation of mouse neural stem cells using TGF-ß and FCS for differentiation induction. Array data were deposited in GEO (Gene Expression Omnibus, NCBI) under accessi...

BACKGROUND CONTEXT Systematic reviews of randomized controlled trials suggest that spinal manipulative therapy (SMT) is efficacious for care of cervicogenic headache (CGH). The effect of SMT dose on outcomes has not been studied. PURPOSE To compare the efficacy of two doses of SMT and two doses of light massage (LM) for CGH. PATIENT SAMPLE Eighty patients with chronic CGH. MAIN OUTCOME ME...