it is shown that when a special vertex stretching is applied to a graph, the cochordal cover number of the graph increases exactly by one, as it happens to its induced matching number and (castelnuovo-mumford) regularity. as a consequence, it is shown that the induced matching number and cochordal cover number of a special vertex stretching of a graph g are equal provided g is well-covered bipa...

‎let $s$ be a subset of a finite group $g$‎. ‎the bi-cayley graph ${rm bcay}(g,s)$ of $g$ with respect to $s$ is an undirected graph with vertex set $gtimes{1,2}$ and edge set ${{(x,1),(sx,2)}mid xin g‎, ‎ sin s}$‎. ‎a bi-cayley graph ${rm bcay}(g,s)$ is called a bci-graph if for any bi-cayley graph ${rm bcay}(g,t)$‎, ‎whenever ${rm bcay}(g,s)cong {rm bcay}(g,t)$ we have $t=gs^alpha$ for some $...

background : many types of cancer cells require a supply of fatty acids (fa) for growth and survival, lpl, in the presence of triglyceride-rich lipoproteins, accelerates the growth of these cells. recent evidence shows that lpl plays important roles in inflammation and obesity, implies that it is an appropriate general target for chemo preventive and chemotherapeutic agents. thus, we reported l...

the concept of the bipartite divisor graph for integer subsets has been considered in [‎graph combinator., ‎ 26 (2010) 95--105‎.]. ‎in this paper‎, ‎we will consider this graph for the set of character degrees of a finite group $g$ and obtain some properties of this graph‎. ‎we show that if $g$ is a solvable group‎, ‎then the number of connected components of this graph is at most $2$ and if $g...

a multicone graph is defined to be join of a clique and a regular graph. a graph $ g $ is  cospectral with  graph $ h $ if their adjacency matrices have the same eigenvalues. a graph $ g $ is  said to be  determined by its spectrum or ds for short, if for any graph $ h $ with $ spec(g)=spec(h)$, we conclude that $ g $ is isomorphic to $ h $. in this paper, we present new classes of  multicone g...

The risk of human breast cancer is concerned to cumulative exposure of the breast cells to endogenous estrogens. Strategies aiming at reducing the production of estrogens may be useful for the prevention of estrogens-related breast cancer. Several natural products with plant origin have the potential value as chemo-preventive or therapeutic agents in cancer. Flavonoids, the natural polyphenol c...

Oxidative stress has become an important subject for terrestrial and aquatic toxicology. The trace element selenium has been demonstrated in chemo-prevention and drug-resistance through reduction of oxidative stress. Selenium compounds could prevent damage to the unsaturated fatty acid of subcellular membranes by lipid peroxidation induced by free radicals in fish.  

Exploiting drug polypharmacology to identify novel modes of actions for drug repurposing has gained significant attentions in the current era of weak drug pipelines. From a serendipitous to systematic or rational ways, a variety of unimodal computational approaches have been developed but the complexity of the problem clearly needs multi-modal approaches for better solutions. In this study, we ...

Preclinical studies suggest that fasting prior to chemotherapy may be an effective strategy to protect patients against the adverse effects of chemo-toxicity. Fasting may also sensitize cancer cells to chemotherapy. It is further suggested that fasting may similarly augment the efficacy of oncolytic viral therapy. The primary mechanism mediating these beneficial effects is thought to relate to ...