OBJECTIVE To study the effect of vaccination on mortality before 2 years of age in a developing country. DESIGN Prospective cohort study. SETTING Rural communities in Burkina Faso. PARTICIPANTS 9085 children born in the study area between 1985 and 1993. MAIN OUTCOME MEASURE Child death rate. RESULTS Mortality before 2 years of age was lower in children who had been vaccinated: those v...

introduction: poisoning is one of the most common medical emergencies especially in children. it leads to hospitalization,and is the most important reason of mortality in children. it is much more common in younger children . studies have shown that approximately 80% of the  patients  younger than 6 years old. this study is conducted to  evaluate poisoning  in children hospitalized in razi & sh...

EPIDEMIOLOGY Globally, 3.7 million children died within the neonatal period in 2004 with 25-45% of deaths occurring within the first day after in 2004.2 Over 50% of the world's infant mortality occurs in the developing and tropical countries and is related to the prevalent high neonatal mortality rate.1 A similar trend was observed in maternal mortality in the sub-Saharan region with mortality ...

OBJECTIVES Improvements in survival for children with sickle cell disease (SCD) during the last 30 years have been well established. Whether similar improvements for adults with the disease have occurred is unknown. We investigated mortality rates for children and adults with SCD. METHODS We used the National Center for Health Statistics multiple-cause-of-death files to examine age at death a...

OBJECTIVE To examine in a randomised trial whether a 25% difference in mortality exists between 4.5 months and 3 years of age for children given two standard doses of Edmonston-Zagreb measles vaccines at 4.5 and 9 months of age compared with those given one dose of measles vaccine at 9 months of age (current policy). DESIGN Randomised controlled trial. SETTING The Bandim Health Project, Gui...

BACKGROUND In Guinea-Bissau we conducted three trials of neonatal vitamin A supplementation (NVAS) from 2002 to 2008. None of the trials found a beneficial effect on mortality. From 2003 to 2007, an early measles vaccine (MV) trial was ongoing, randomizing children 1:2 to early MV at 4.5 months or no early MV, in addition to the usual MV at 9 months. We have previously found interactions betwee...

To examine the relationship between birth characteristics and childhood cancer mortality, a retrospective cohort study of Korean children was conducted using data collected by the national birth register between 1995 and 2006, which were then individually linked to death data. A cohort of 6,479,406 children was followed from birth until their death or until December 31, 2006. Poisson regression...

background nosocomial infections (nis) are an important public health problem worldwide, particularity in the intensive care units (icus). objectives the current study aimed to detect and highlight nis as the critical factor in increasing mortality and morbidity to clarify the current health priorities and challenges in iran. patients and methods it was a retrospective study on 376 selected pat...

background: improving maternal health is one of the eight millennium development goals (mdgs) aimed at improving maternal healthcare and reducing maternal mortality. the utilization of maternal health services is influenced by several factors that need to be better understood. the objective of this study was to estimate the role of socio-economic position as a determinant of the utilization of ...