Since 1970s the evaluation and treatment of bile duct lesions have been accomplished mostly by endoscopic retrograde cholangiopancreatography (ERCP). However, neither ERCP nor other imaging procedures (e.g., endoscopic ultrasound) allow for safe diagnosis of these lesions. Since the emergence of the fiberoptic SpyGlass Direct Visualization System (SDVS) (Boston Scientific, Natick, Massachusetts...