Regression mechanism of Ethyl 2-(p-chlorophenoxy) isobutyrate (CPIB) in the arterial wall was studied for elucidation in terms of fatty acid-compositional change in cholesterol-fed rabbits. The following evidence was obtained: (1) The amount of cholesterol and cholesteryl ester in the atheromatous aorta were reduced after CPIB treatment. (2) CPIB resulted in a significant increase in the ratio ...

An intracellular protein accelerates the transfer of triglyceride and cholesteryl ester. The fraction of phospholipid transferred was much less than for the less polar lipids. A rich source of this activity was obtained from low ionic strength washes of liver microsomes. The protein was partially purified by column chromatography on Bio-Gel A-5m and hydroxylapatite. The elution position of the ...

PERSPECTIVES AND SUMMARY ............................... .... ....................................... 224 UPTAKE OF LIPOPROTEIN-BOUND CHOLESTEROL BY MACROPHAGES ................................................................................................ 226 Receptor for Acetyl-LDL .......................................................................................... 227 Receptor for LDL...

In previous papers (1,2) the thermotropic properties and the kinetics of the bulk polymerization of the mesomorphic monomer cholesteryl acrylate have been described. In addition to cholesteryl acrylate, the methacrylate was prepared, as well as the respective acrylic methacrylic acid ester of cholestanol. We now wish to report the properties of these monomeric esters and the results of their po...

White Carneau (WC) pigeons are susceptible to the development of aortic atherosclerosis, whereas Show Racer (SR) pigeons are resistant, even though there are no differences in the known risk factors, including plasma cholesterol levels, lipoproteins, blood pressure, etc. Although this suggests that the difference in atherosclerosis susceptibility between WC and SR pigeons may be mediated at the...