Ectopic production and secretion of hormones by a wide variety of tumors has been known for decades. Initially, ectopic hormone secretion was recognized by signs and symptoms of excess circulating biologically active hormone. With development of more sophisticated assay techniques, biologically inactive fragments and "big" forms of authentic hormones have been identified in these syndromes. Rec...

The present study is designed to elucidate certain biological characteristics of urinary chorionic gonadotropin and to see what differences could be demonstrated between HCG in normal pregnancy and in the trophoblastic diseases. We have attempted the biological characterization of HCG using crude HCG and the purified HCG (12 ,000 I.U./mg) by zone electrophoresis on starch grain and chromatograp...

introduction: ectopic molar pregnancy is a rare occurrence and consequently not often considered as a diagnostic possibility. in this article, an attempt was made to stress on the need for histopathological examination and follow up of every case of ectopic pregnancy. this was substantiated with the help of a case report. case presentation: a 30-year-old gravida 4, para 3, pregnant woman with a...

background: considering the effect of preterm delivery in morbidity and mortality of newborns, its precaution and prevention is so important. objective: to investigate the association between second trimester maternal serum biomarkers (human chorionic gonadotropin, alpha-fetoprotein, non-conjugated estrogen, inhibin a) and pre-term delivery. materials and methods: this is a historical cohort st...

Given its rustic nature, its butchery quality and its trypanotolerance, the N’Dama breed represents a significant potential for developing African cattle breeding [6]. To date, its zootechnical performance and reproductive characteristics have been the subject of relatively little work. The use of selection programmes and artificial insemination are highly significant challenges for developing ...

The unsatisfactory standardization of many immunoassays is fairly well recognized, but the problem is hard to tackle (1 ). Recently, studies on the performance of immunoassays for testosterone in female serum (2 ) and for urinary cortisol (1 ) have revealed that the quality of some widely used assays is totally unsatisfactory. The quality of assays for human chorionic gonadotropin (hCG) has als...

nonsignificant differences between cutoffs for serum and plasma and between assays are encouraging regarding the ease of interpretation by clinicians and laboratories. Also encouraging were improvements in the analytical sensitivity of these newergeneration assays. Interestingly, only 3 samples were identified as above the 99th percentile by all 3 assays. The mechanisms responsible for this lac...