نتایج جستجو برای: choroidal neovascularization

تعداد نتایج: 17766  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Hongjun Du Xufang Sun Monica Guma Jing Luo Hong Ouyang Xiaohui Zhang Jing Zeng John Quach Duy H Nguyen Peter X Shaw Michael Karin Kang Zhang

Age-related macular degeneration (AMD) is the leading cause of registered blindness among the elderly and affects over 30 million people worldwide. It is well established that oxidative stress, inflammation, and apoptosis play critical roles in pathogenesis of AMD. In advanced wet AMD, although, most of the severe vision loss is due to bleeding and exudation of choroidal neovascularization (CNV...

2015
Sharat Hegde Nidhi Relhan Avinash Pathengay Abhishek Bawdekar Himadri Choudhury Animesh Jindal Harry W Flynn

BACKGROUND Choroidal neovascularization during the active stage of Toxoplasma retinochoroiditis is an uncommon clinical presentation. The authors retrospectively reviewed medical charts of patients with coexisting choroidal neovascular membrane and active Toxoplasma retinochoroiditis. FINDINGS Three patients presented with coexisting choroidal neovascular membrane and active Toxoplasma retino...

Journal: :Investigative ophthalmology & visual science 2009
Marisol del Valle Cano Emmanouil D Karagiannis Mohamed Soliman Belal Bakir Wenjuan Zhuang Aleksander S Popel Peter L Gehlbach

PURPOSE Ocular neovascularization is the primary cause of blindness in a wide range of prevalent ocular diseases including proliferative diabetic retinopathy, exudative age-related macular degeneration, and retinopathy of prematurity, among others. Antiangiogenic therapies are starting to give promising results in these diseases. In the present study the antiangiogenic potential of an 18-mer pe...

2012
X. F. Steven Zheng

(AMD) is a leading cause of irreversible blindness among people of 50 year or older. During AMD, vascular endothelial growth factor (VEGF) may become elevated, causing choroidal neovascularization (CNV) and vascular permeability and fragility. Choroidal neovascularization can break in Bruch's membrane, resulting in subretinal hemorrhage, fluid exudation, detachment of the retinal pigment epithe...

2012
Kei Takayama Tosio Enoki Teruo Kojima Sho Ishikawa Masaru Takeuchi

Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is a rare disorder that sometimes causes sudden subretinal and/or vitreous hemorrhage. Choroidal neovascularization is involved in the pathogenesis, but the etiology is unknown. Treatments with photocoagulation, cryopexy, and intravitreal bevacizumab injection have been reported. However, the therapeutic effect of intravitreal injection...

Journal: :Archives of ophthalmology 2011
Yuhong Chen Jiexi Zeng Chao Zhao Kevin Wang Elizabeth Trood Jeanette Buehler Matthew Weed Daniel Kasuga Paul S Bernstein Guy Hughes Victoria Fu Jessica Chin Clara Lee Maureen Crocker Matthew Bedell Francesca Salasar Zhenglin Yang Michael Goldbaum Henry Ferreyra William R Freeman Igor Kozak Kang Zhang

OBJECTIVES To evaluate the independent and joint effects of genetic factors and environmental variables on advanced forms of age-related macular degeneration (AMD), including geographic atrophy and choroidal neovascularization, and to develop a predictive model with genetic and environmental factors included. METHODS Demographic information, including age at onset, smoking status, and body ma...

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