Ayurveda is an ancient science of life that uses a wide range formulations or herbal compounds to treat various diseases. Each drug must be scientifically, pre-clinically, and clinically evaluated in order gain global acceptance. As part the safety evaluation process, regulatory authorities around world require data on new genotoxic potential.MusalyadiChurna(MSDC) classical Ayurvedic formulatio...

NUTRALYS Pea Protein Isolate, a protein supplement, is a high-quality source of protein which is primarily emulsifying functional protein. We evaluated the genotoxic potential of NUTRALYS isolated from dry yellow pea, using three established genotoxicity tests (AMES test in vitro chromosomal aberration test, and in vivo micronucleus test) employing OECD guidelines under GLP conditions. In the b...

Note Chromosomal deletions are among the most common genetic events observed in hematologic malignancies; loss of genetic materiel is regarded as a hallmark of putative tumor suppressor gene localization. Deletions 13q occurs in lymphoid neoplasias: see del(13q) in non-Hodgkin's lymphoma and del(13q) in chronic lymphoproliferative diseases. In myeloid disorders, the most frequently reported del...

Higher plants, an important material for genetic tests to monitor various pollutant present in the environment. Among the plant species, Alium cepa has been used to evaluate chromosome aberrations and disturbances in the mitotic cycle. Now days, it has been used to assess a great number of genotoxic/antigenotoxic agents, which contributes to its increasing application in environmental monitorin...

Abstract. Haq FAN, Etikawati N, Solichatun. 2023. Effect of cypermethrin insecticide on root chromosome morphometry scallion (Allium fistulosum). Cell Biol Dev 7: 14-21. Farmers in Tawangmangu, Karanganyar, Central Java, Indonesia, commonly use a pesticide known as whenever growing fistulosum L.). If used at excessive levels, can be fatal to plants. Chromosome morphological changes are an indic...

Epilepsy is among the most common findings associated with chromosome aberrations, particularly those involving autosomal chromosome imbalances. Most chromosome aberrations can be associated with different seizure types, but there are a few aberrations featuring specific seizure and electroencephalographic (EEG) patterns. The analysis of electro-clinical patterns associated with chromosomal abe...