BACKGROUND The aim of our work was to investigate the effects ofω -3 polyunsaturated fatty acids on apoptosis and granzyme B, perforin, and cation-independent mannose 6-phosphate/insulin-like growth factor receptor (CI-MPR) expression of intestinal epithelial cells of chronic rejection after small intestinal transplantation. METHODS Small bowel transplantation was performed in a rat combinati...

Early renal transplant dysfunction can be caused by acute rejection, acute tubular necrosis (ATN), infection, ciclosporin toxicity, bleeding, urethral obstruction, urinary leak, lymphocele and thrombosis [1]. Prompt treatment of early allograft dysfunction is essential and therefore accurate diagnosis mandatory. We describe a patient with an unusual cause of allograft dysfunction, which was res...

Polyomavirus BK-associated nephropathy (PyVAN) is the main infectious cause of allograft damage after kidney transplantation. A number of studies revealed an association between the presence of BKV-specific cellular immunity and BK viral clearance, with patients failing to recover specific T cells progressing to PyVAN. Evolution to allograft dysfunction can be prevented by restoration of BKV-sp...

Whether antibody-mediated rejection after lung transplantation exists as an entity is debated by immunologists, histopathologists, and clinicians, without a strong consensus regarding diagnostic characteristics despite an increasing body of evidence that attests to a significant role in other solid organ transplant disciplines. Evidence for and against the protean manifestations of antibody-med...

BACKGROUND Bronchiolitis obliterans syndrome (BOS) with small-airway pathology and obstructive pulmonary physiology may not be the only form of chronic lung allograft dysfunction (CLAD) after lung transplantation. Characteristics of a form of CLAD consisting of restrictive functional changes involving peripheral lung pathology were investigated. METHODS Patients who received bilateral lung tr...

OBJECTIVES Our previous study demonstrated that Ligustrazine reduced renal dysfunction associated with ischemia-reperfusion injury in mice. In this study, we investigated whether Ligustrazine herbal injection had any preventive and therapeutic effectiveness against chronic allograft nephropathy in rats. METHODS Male Lewis rats that received left renal grafts from male Fisher 344 rats were ran...

Cite this article: Sato M (2014) Chronic Lung Allograft Dysfunction After Lung Transplantation and Late Onset Non-infectious Pulmonary Complications After Hematopoietic Stem Cell Transplantation: Are they Mirror Images? Clin Res Pulmonol 2(1): 1014. *Corresponding author Masaaki Sato, Department of Thoracic Surgery, Kyoto University Hospital, 54Kawara-chyo, Sakyo-ku, Kyotocity, Kyoto606-8507, J...