In the May issue of the Journal, King and Moores1 presented a very nice overview of asthma phenotypes and disorders that mimic asthma. That article was followed by a paper by McCormack and Enright2 that reviewed the process of making a diagnosis of asthma, including a brief overview of the differential diagnosis of asthma. I respectfully submit that missing from both papers is a description of ...

The effect of sauna on tracheobronchial clearance was studied in five male patients with chronic bronchitis by a radioaerosol technique. No enhancement of tracheobronchial clearance could be detected.

An analysis of the plasma proteins in the sol phase of sputum was carried out using quantitative cross immunoelectrophoresis. The average concentrations of nine plasma proteins were estimated in the sol phase of sputum specimens from 30 patients with chronic bronchitis and the values were compared with the concentrations of these proteins in saliva and serum specimens from the same group of pat...

and on 20,000 Minneapolis public school children. Besides the 'determination of the thoracic index {i.e., the" ratio of the depth of the chest to its width), the length-width index, the length-depth index and the size of the subcostal angle, the vital capacity was measured. The author refers to the popular and erroneous idea that the healthy chest is 'round and deep and the tuberculous chest fl...

The development of animal model systems in which hypotheses regarding a human disease counterpart can be tested should enable the independent evaluation of variables in a multifactorial system. This is particularly germane in a consideration of chronic obstructive lung disease since chronic bronchitis and emphysema may occur in combination or independently of the other, and since a number of ag...

In Canada, USA and 9 Western European Countries, 121 respiratory physicians responded to an English language questionnaire asking them to state how they would investigate, treat and label four model patients, chosen to represent well-recognized patterns of clinical features of chronic airflow obstruction. Selection of further investigations appeared to be determined more by the probable diagnos...

PURPOSE Our objective was to assess the prevalence of chronic bronchitis and chronic obstructive pulmonary disease (COPD) and their correlates among a Lebanese nonsmoker group. MATERIAL AND METHODS A cross-sectional study was conducted between October 2009 and September 2010, using a multistage cluster sample throughout Lebanon including Lebanese residents aged 40 years and above with no excl...

Asthma is characterized by narrowing of the airways in response to various stimuli and the presence of airway inflammation of varying degree. Unlike the more fixed or permanent airflow obstruction typical of chronic bronchitis, emphysema, cystic fibrosis, bronchiectasis, and bronchiolitis, the airflow obstruction associated with asthma may be completely reversible [see 14:III Chronic Obstructiv...

Club cell protein (CC16 in humans) plays a crucial role in maintaining homeostasis of the airway epithelium [1] and has anti-inflammatory activity in the lung [2]. Serum CC16 levels are low in cigarette smokers [3] and increase following smoking cessation [4], but patients with chronic obstructive pulmonary disease (COPD) show progressive decrease in CC16 with disease severity [5]. Thus, althou...

70S CHEST, VOL. 63, NO. 4, APRIL 1973 SUPPLEMENT Reference to Lesions Found in Asymptomatic Chronic Bronchitis without Emphysema w. M. Thurlbeck, M.D.#{176} W e have measured and counted conducting aimways less than 2 mm in internal diameter ( “small airways” ) in the lungs of patients with and without chronic bronchitis, and with and without emphysema. Eighteen patients without chronic bronchi...