background hyponatremia is a common disorder in patients with brain injury. it can result in acute and chronic complications providing this electrolytic disorder is not diagnosed and treated in due time. objectives the aim of this study was to evaluate the prevalence of hyponatremia in 95 patients with brain injury hospitalized in the intensive care unit in shahid beheshti hospital of kashan un...

Traumatic brain injury (TBI) is a global health concern that typically causes emotional disturbances and cognitive dysfunction. It elicits a complex secondary injury response, with neuroinflammation as a crucial central component. Secondary pathologies following TBI may be associated with chronic neurodegenerative disorders and an enhanced likelihood of developing dementia-like disease in later...

BACKGROUND Survivors of acute kidney injury are at an increased risk of developing irreversible deterioration in kidney function and in some cases, the need for chronic dialysis. We aimed to determine predictors of chronic dialysis and death among survivors of dialysis-requiring acute kidney injury. METHODS We used linked administrative databases in Ontario, Canada, to identify patients who w...

Spontaneous perforation of the sigmoid colon or rectom is defined as a sudden perforation of the colon in the absence of diseases such as tumors, diverticulosis or external injury. It is a very rare finding, and if neglected, results in severe peritonitis and high mortality. The causes of this rare condition are numerous, and in this case it might be due to the chronic constipation induced by a...

Physicians and other therapists continue to grapple in daily practice with the controversies of the late whiplash syndrome. For decades much of the debate and the approach to this controversial syndrome has centred on the natural history of and progression to chronic pain after acute whiplash injury. Recognising that there is recent epidemiological data that defines the natural history of the a...

Physicians and other therapists continue to grapple in daily practice with the controversies of the late whiplash syndrome. For decades much of the debate and the approach to this controversial syndrome has centred on the natural history of and progression to chronic pain after acute whiplash injury. Recognising that there is recent epidemiological data that defines the natural history of the a...

INTRODUCTION Rotator cuff tears of the shoulder are a common cause of pain and disability and surgical repair of these injuries is plagued with recurrent tear rates ranging from 20-70% [1]. The time from onset of injury to time of surgical repair is one important factor in repair outcome [2]. Animal models have recently been developed to address hypotheses related to rotator cuff tendon to bone...

Adiponectin is an adipocyte-derived circulating protein with beneficial effects on injured livers. Adiponectin-deficient (adipo(-/-)) mice develop enhanced liver fibrosis, suggesting that adiponectin could be a therapeutic target for liver injury. In the present study, we investigated the protective role of ADP355, an adiponectin-based active short peptide, in thioacetamide (TAA)-induced acute ...

Professional boxing is associated with a risk of chronic neurological injury, with up to 20-50% of former boxers exhibiting symptoms of chronic brain injury. Chronic traumatic brain injury encompasses a spectrum of disorders that are associated with long-term consequences of brain injury and remains the most difficult safety challenge in modern-day boxing. Despite these concerns, traditional gu...

background: hyperglycemia is frequently encountered in critically ill patients and has been shown to contribute to both morbidity and mortality. we aimed to study the predictive role of blood glucose level in clinical outcomes of mechanically ventilated patients with traumatic brain injury during intensive care unit (icu) stay and to explore its relationship with glasgow coma scale (gcs) and ac...