Epidemiology of Chronic Kidney Disease Chronic kidney disease (CKD) is a major global health problem. It is defined by decreased kidney function (characterized by a reduced estimated glomerular filtration rate [eGFR] <60 mL/min per 1.73 m) and kidney damage characterized by albuminuria or proteinuria. To standardize definitions and facilitate risk stratification, 5 different stages of severity ...

Introduction Numerous published studies identify acute kidney injury (AKI) as an independent risk factor for developing incident chronic kidney disease (CKD), progressive CKD, end-stage renal disease (ESRD), and other important non-renal outcomes with substantial public health implications. A recent meta-analysis showed that use of highchloride crystalloids in critically ill patients was associ...

Diet is one of the largest modifiable risk factors for chronic kidney disease (CKD)-related death and disability. CKD is largely a progressive disease; however, it is increasingly appreciated that hallmarks of chronic kidney disease such as albuminuria can regress over time. The factors driving albuminuria resolution remain elusive. Since albuminuria is a strong risk factor for GFR loss, modifi...

We reported a case of adynamic bone disease (ABD) in an older woman with chronic kidney disease, stage-4 (CKD-4), estimate 29ml/min glomerular filtration rate (eGFR). Similarly, the patient presented pain and osteoporosis as well intact parathyroid hormone (PTH) was suppressed (&lt;6ng/dl) secondary to use vitamin D analogs for hyperparathyroidism (SHPT) CKD. Furthermore, hypercalcemia (11.1 mg...

BACKGROUND AND OBJECTIVES Awareness of chronic kidney disease (CKD) among providers and patients is low. Whether clinical cues prompt recognition of CKD is unknown. We examined whether markers of kidney disease that should trigger CKD recognition among providers are associated with higher individual CKD awareness. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS CKD awareness was assessed in 185...

Chronic kidney disease (CKD) influencesmore than 10% of adult population worldwide (Hill et al., 2016). Among this population, many of them could progress into the end stage renal disease and finally require the therapies of kidney transplantation or dialysis. Thus, it is of vital importance in retarding the progression of CKDs during the early stage (stages 1–2) via an effective intervention. ...

UNLABELLED Chronic kidney disease (CKD) and end-stage renal disease (ESRD) have emerged as a worldwide public health problem. Due to the remarkably higher incidence and prevalence of this chronic disease in Taiwan than in other countries, CKD/ESRD has contributed to a significant health burden in Taiwan. Patients with CKD/ESRD have an increased risk of coronary artery disease (CAD) and acute co...

BACKGROUND Chronic kidney disease (CKD) affects up to 16% of the adult population and is associated with significant morbidity and mortality. People at highest risk from progressive CKD are defined by a sustained decline in estimated glomerular filtration rate (eGFR) and/or the presence of significant albuminuria/proteinuria and/or more advanced CKD. Accurate mapping of the bio-clinical determi...

Background: Chronic kidney disease (CKD) affects up to 16% of the adult population and is associated with significant morbidity and mortality. People at highest risk from progressive CKD are defined by a sustained decline in estimated glomerular filtration rate (eGFR) and/or the presence of significant albuminuria/proteinuria and/or more advanced CKD. Accurate mapping of the bio-clinical determ...

results bw was lower for the 5/6 nx group rats after the operations compared with the bw of those in the sham operation group. furthermore, the 5/6 nx group showed elevations in blood pressure, cr, bun, alt, and ast levels compared with the sham group over the course of time. conclusions in summary, ckd induced by the 5/6 nx model caused hypertension and increased serum levels of cr, bun, alt, ...