BACKGROUND The fusiform gyrus (FG), or occipitotemporal gyrus, is thought to subserve the processing and encoding of faces. Of note, several studies have reported that patients with schizophrenia show deficits in facial processing. It is thus hypothesized that the FG might be one brain region underlying abnormal facial recognition in schizophrenia. The objectives of this study were to determine...

BACKGROUND The effects of creatine on brain metabolism and the potential cognitive enhancing properties of this compound raise the possibility of developing a new augmentation therapeutic strategy in schizophrenia especially in patients demonstrating negative and cognitive symptomatology. METHODS Seven inpatients with chronic schizophrenia presenting with treatment resistant negative symptoms...

OBJECTIVE The authors performed a longitudinal study of the effects on thalamic volume of switching from typical to atypical antipsychotic medications. METHOD Magnetic resonance imaging scans were acquired from 10 subjects with chronic schizophrenia taking typical antipsychotics and 20 healthy volunteers. Subjects with schizophrenia were switched to olanzapine; both groups were rescanned. R...

Stigmatization represents a chronic negative interaction with the environment that most people with a diagnosis of schizophrenia face on a regular basis. Different types of stigma-public stigma, self--stigma, and label avoidance--may each have detrimental effects. In the present article, the possible consequences of stigma on onset, course, and outcome of schizophrenia are reviewed. Stigmatizat...

Theoretical models suggest that it is the interplay between social cognitive processes result in adaptive functioning schizophrenia. This study explored relative contributions of, and between, empathy, affective theory of mind (ToM), neurocognition, severity clinical symptoms, predicting individuals with Clinical participants (early schizophrenia n = 26, chronic 32) were administered an ecologi...

BACKGROUND Schizophrenia is a serious, chronic, and often debilitating neuropsychiatric disorder. Its causes are still poorly understood. Besides genetic and non-genetic (environmental) factors are thought to be important as the cause of the structural and functional deficits that characterize schizophrenia. This study aimed to compare Toxoplasma gondii infection between schizophrenia patients ...

Since the discovery of first antipsychotic in 1952, many drugs have been developed, each with different pharmacokinetic and pharmacodynamic properties. The pharmacological heterogeneity should allow a personalized drug prescription adapted to clinical picture schizophrenia. Schizophrenia is chronic disease, during which 3 stages intervention can be identified: episode psychotic (FEP), phase the...

Inflammation may play a crucial role in the pathogenesis of schizophrenia. However, the association between chronic inflammation and health outcomes in schizophrenia remains unclear, particularly for patient-reported outcomes. The aim of this study was to investigate the relationship between quality of life (QoL) and chronic inflammation assessed using C -Reactive Protein (CRP) in patients with...