abstract background and objective: iranian traditional medicine (itm) has a long history in the prevention and treatment of diseases. clinical uses, side effects, and toxic effects of many singular and compounds were known to scientists of itm and articular books on toxicology and detoxification of drugs has been written by scientists, but their measurement tools to evaluate chronic toxicity of...

stachys lavandulifolia is used as the herbal tea and its wide and potent medical effects have been reported for the extract in animal studies. this study aimed to find the safety profile of the extract to find the appropriate doses for further human studies. the aerial parts of the plant were air-dried and the hydroalcoholic extract was obtained and concentrated by percolation method with 140 m...

PURPOSE It is well known that acute exposure to high concentrations of glutamate is toxic to central mammalian neurons. However, the effect of a chronic, minor elevation over endogenous glutamate levels has not been explored. The authors have suggested that such chronic exposure may play a role in glaucomatous neuronal loss. In the current study, they sought to explore whether a chronic, low-do...

Extracts of Phaleria macrocarpa have been used for years in traditional medicine and evaluated scientifically as well. This study aimed to evaluate the chronic toxicity level nano herbal its effect on changes hematology, biochemistry, electrolytes, organ histopathology. High Energy Milling (HEM) produced . By giving at doses 300, 600, 900 mg/kg BW 56 days, mice’s blood was collected hematologic...