Migraine has been connected to hypoperfusion and cerebral ischemia in several studies [1,2]. Moreover, increased prevalence of silent white mater changes and even minute cerebral infarcts is reported in migraineurs [1]. Cucchiara and Detre proposed that migraine can cause or result from cerebral ischemia [3]. The basis of their assumption emerged from observations that catheter angiography can ...

A numerical model based on one-dimensional balance laws and ad hoc zero-dimensional boundary conditions is tested against experimental data. The study concentrates on the circle of Willis, a vital subnetwork of the cerebral vasculature. The main goal is to obtain efficient and reliable numerical tools with predictive capabilities. The flow is assumed to obey the Navier-Stokes equations, while t...

BACKGROUND AND PURPOSE The circle of Willis (CW) is considered an important collateral pathway in maintaining adequate cerebral blood flow in patients with internal carotid artery (ICA) obstruction. We aimed to investigate the anatomic variation of the CW in patients with severe symptomatic carotid obstructive disease and to analyze diameter changes of its components in relation to varying grad...

Objective: The pathogenesis of cerebral white matter lesion (WML) may be associated with chronic cerebral hypoperfusion. Incomplete circle of Willis (CoW) and cerebral artery stenosis (CAS) may contribute to chronic cerebral hypoperfusion. This study aimed to investigate whether incomplete CoW and CAS were associated with WML by a prospective study. Methods: 102 patients were enrolled in this s...

Static elastic properties were obtained from pressure, volume, and length measurements of 34 isolated human cerebral arteries from 23 circles of Willis of patients aged 23-76 years. No significant difference in initial or final elastance was observed with age or branch in the circle of Willis. Twenty-four of the arteries from 18 circles of Willis were then subjected to transmural pressures of 2...