Abstract Macrophage inflammatory protein-3, or MIP-3α, is a chemokine that highly expressed in gliomas, with expression progressively increasing tumor grade. It one of the top genes pseudopalisading and perinecrotic zones glioblastoma (GBM) as chemokine, can greatly influence tumor-immune interactions. The receptor for CCR6, found on variety GBM-infiltrating immune subsets such γδ T cells, conv...

The sequestration of rat leukocytes and bone marrow cells by the lung vasculature was studied using an isolated perfused rat lung preparation. The passage of latex particles of 7.6 µm in diameter and non-hematopoietic cells through the lung blood vessels was also studied. Leukocytes and bone marrow cells were reversibly sequestered from circulation, whereas, latex particles and non-hematop...