Heart failure and persistent respiratory insufficiency associated with patent ductus arterioeus occur frequently in lowbirth-weight infants.'-" Surgical ligation of the patent ductus arteriosus (PDA) has been advocated when conservative medical management fails.3 '7 This report describes our experience with 14 patients averaging a weight of less than 1500 grams each who were presented for thora...

The combination of patent (luctus arteriosus land coarctation of the aorta poses special anatomic, physiologic and surgical proldems. An experience with 14 such cases is presented, wVhich suggests that pulmonary hypertension occurs frequently in these cases. Physiologic data in cases having coarctation of the aorta, patent (luctus arteriosus and pulmonary hypertension that underwent cardiac cat...

We describe the development of hemolysis from moderate residual shunting across a patent ductus arteriosus following coil embolization. The fall in hemoglobin levels from 11.6 to 6.0 gm/dl necessitated a second coil procedure which resulted in complete closure of the residual shunting and resolution of hemolysis. Therefore, appearance of anemia following coil embolization of patent ductus arter...

The adrenergic innervation of the patent human ductus arteriosus was studied using the Falck-Hillarp fluorescent histochemical method for the localization of monoamines. Few adrenergic terminals were demonstrated in the muscular layers of the patent ductus arteriorms in 14 specimens examined. The innervation to the adventitia was sparse to moderate. The possibility that a developmental abnormal...

Contractile responses of rings of ductus arteriosus from fetal and neonatal guinea pigs were studied in buffered Krebs-Henseleit solutions of various oxygen tensions. Oxygen-induced contraction of ductus arteriosus increased with gestational age, peaking at term and attenuating within 24 h after birth. Contractions of ductus in response to potassium were not different in term and preterm fetuse...

T HE PRESENCE of an asymptomatic patent ductus arteriosus is usually suspected on the basis of auscultatory findings, and the diagnosis is supported by electrocardiography and roentgenography. Other vascular and cardiac lesions that produce continuous murmurs to the left of the upper sternum are usually symptomatic and are associated with additional changes requiring cardiac catheterization and...

The impression that has been gathered from a perusal of the available literature is that a patent ductus arteriosus as a sole abnormality is comparatively rare. In Abbott's' coliected series of 850 cases there were but 73, and in Laubry and Pezzi's2 well-known work the lesion is said to be rare. Recently Perry3 in a review of congenital heart lesions in Bristol school children found, amongst 12...

The impression that has been gathered from a perusal of the available literature is that a patent ductus arteriosus as a sole abnormality is comparatively rare. In Abbott's' coliected series of 850 cases there were but 73, and in Laubry and Pezzi's2 well-known work the lesion is said to be rare. Recently Perry3 in a review of congenital heart lesions in Bristol school children found, amongst 12...