The effect of diastolic dysfunction (DD) on the timing of left ventricular (LV) diastolic longitudinal and circumferential expansion and their load dependence is not known. This study evaluated the timing of the peak early diastolic LV inflow velocity (E), mitral annular velocity (e'), and longitudinal and circumferential global strain rates (SRE) in 161 patients in sinus rhythm. The intraventr...

The parametric representation and aerodynamic shape optimization of a three-dimensional circular-to-rectangular transition nozzle designed built using control lines distributed along the circumferential direction were investigated in this study. A surrogate model based on class/shape transformation, principal component analysis radial basis neural network was proposed with fewer design paramete...

The rheological behaviour of a dense granular bed under dynamic conditions is investigated by simulating flow in the FT4 powder rheometer using Discrete Element Method. distribution prevailing stresses and strain rates bed, their dependence on material properties blade operational conditions, are analysed. shear stress was found to be approximately constant radial direction along but dissipates...

Abstract This paper introduces the Bayesian mass average and details its computation. Owing to complexity of flow in an engine limited instrumentation precision sensor apparatus used, it is difficult rigorously calculate averages. Building upon related work, this views any thermodynamic quantity’s spatial variation at axial plane (or a rig) as Gaussian random field. In cases where flowrate cons...

The continual reassessment method (CRM) enables full and efficient use of all data and prior information available in a phase I study. However, despite a number of recent enhancements to the method, its acceptance in actual clinical practice has been hampered by several practical difficulties. In this paper, we consider several further refinements in the context of phase I oncology trials. In p...

The in vivo circumferential strain has a small variation throughout the vascular system (aorta to arterioles). The axial strain has also been shown to be nearly the same as the circumferential strain under physiological loading. Since the endothelium is mechanically much softer than the media-adventitia in healthy arteries, the porcine intima was considered as a mechanically distinct layer from...

AIM We evaluated the validity of circumferential carotid artery strain as a marker for subclinical atherosclerosis and its benefit in addition to carotid intima-media thickness (IMT) to detect high-risk groups. METHODS The study was a cross-sectional study. From April 2007 to July 2008, 1057 patients who had undergone both echocardiography and carotid ultrasonography were consecutively enroll...

BACKGROUND Data on the comparative value of the circumferential pulmonary vein and the segmental pulmonary vein ablation for interventional treatment of atrial fibrillation are limited. We hypothesized that the circumferential pulmonary vein ablation approach was superior to the segmental pulmonary vein ablation approach. METHODS AND RESULTS One hundred patients with highly symptomatic atrial...

BACKGROUND AND PURPOSE Fixation of unstable trochanteric fractures is challenging. Application of a circumferential wire may facilitate bone contact and avoid postoperative fracture displacement. However, the use of circumferential wires remains controversial due to possible disturbance of the blood supply to the underlying bone. We evaluated the results of applied circumferential wires, concen...