Creatine kinase (CK) is an enzyme central to cellular high-energy phosphate metabolism in muscle. To characterize the physiological role of CK in respiratory muscle during dynamic contractions, we compared the force-velocity relationships, power, and work output characteristics of the diaphragm (Dia) from mice with combined myofibrillar and sarcomeric mitochondrial CK deficiency (CK[-/-]) with ...

BACKGROUND We describe a 56-year-old woman admitted to the hospital with a diagnosis of acute myocardial infarction without an increase of serum creatine kinase (CK) activity during her clinical course. She died on the 11th hospital day, and the diagnosis was confirmed by autopsy. The patient had had no previous muscular symptoms. METHODS Expression of the CK-muscle (CK-M) protein in cardiac ...

Decreased cytokinin (CK) export from roots in drying soil might provide a root-to-shoot signal impacting on shoot physiology. Although several studies show that soil drying decreases the CK concentration of xylem sap collected from the roots, it is not known whether this alters xylem CK concentration ([CK(xyl)]) in the leaves and bulk leaf CK concentration. Tomato (Solanum lycopersicum L.) plan...

Ginsenoside metabolite compound K (CK) is a metabolite of ginsenoside, and belongs to dammarane-type triterpene saponins according to its structure. It has been reported that CK exerts anti-inflammatory activity. Our previous studies showed that CK alleviated adjuvant-induced arthritis (AA) and collagen-induced arthritis (CIA) via suppressing T cell activation. Our recent study showed that the ...

BACKGROUND Creatine kinase-MB (CK-MB) elevation after percutaneous coronary intervention (PCI) has been associated with increased risk for mortality. Although most studies have defined periprocedural myocardial infarction (pMI) as an elevation in CK-MB >3× upper limit of normal (ULN), use of different CK-MB assays and variation in site-specific definitions of the ULN may limit the value of such...

Ginsenosides are triterpenoids that are found in P. ginseng; they have numerous important structural, functional and pharmacological properties. In this work, a desolvation method was used to entrap ginsenoside CK within bovine serum albumin (BSA) to form BSA–CK nanoparticles (NPs), which enhance its aqueous solubility and stability. Following purification, the BSA–CK NPs were characterized by ...

OBJECTIVES The study evaluated the incidence and predictors of creatine kinase-MB isoenzyme (CK-MB) elevation after successful coronary intervention using current devices, and assessed the influence on in-hospital course and midterm survival. BACKGROUND The CK-MB elevation after coronary intervention predominantly using balloon angioplasty correlates with late cardiac events of myocardial inf...

Cops and Robbers is a pursuit and evasion game played on graphs that has received much attention. We consider an extension of Cops and Robbers, distance k Cops and Robbers, where the cops win if at least one of them is of distance at most k from the robber in G. The cop number of a graph G is the minimum number of cops needed to capture the robber in G. The distance k analogue of the cop number...