B A C K F I R E ? In late June, Hong Kong media reported China’s PLA-AF (People’s Liberation Army – Air Force) would seek to become a ‘strategic air force’ with the acquisition of the Russian Backfire cited as a core tenet of this fundamental policy change. To best appreciate the potential strategic impact of the Backfire upon the Asia Pacific region it is worth exploring the capabilities of th...

This note describes possible world semantics for a constructive modal logic CK. The system CK is weaker than other constructive modal logics K as it does not satisfy distribution of possibility over disjunctions, neither binary (3(A ∨ B) → 3A ∨ 3B) nor nullary (3⊥ → ⊥). Our intuition is that 3⊥ should not constructively imply ⊥, thus we dispense with both forms of distribution. We are intereste...

Certain types ofmacro-CK, type 1, have been reported to cause false increases in CK-MB by co-migration on electrophoresis (1-3). I report two such cases in which the macroCK was an IgA with anti-CK-BB specificity. According to methods proposed by Medeiros et al. (1), immunoprecipitation and subsequent analysis by elecrophoresis was used to separate interfering macre-CK from CK-MB. CK electropho...

Partindo da análise das manifestações de insatisfação usuários do Spotify no Twitter com o resultado Retrospectiva 2019, pretende-se investigar como a atuação dos algoritmos nas plataformas streaming música pode agenciar prática sonora ouvintes, tendo gosto musical um principais marcadores fruição ambiente digital. O artigo promove resgate conceito performance e busca repensá-lo partir dinâmica...

Video object detection is more challenging compared to image object detection. Previous works proved that applying object detector frame by frame is not only slow but also inaccurate. Visual clues get weakened by defocus and motion blur, causing failure on corresponding frames. Multiframe feature fusion methods proved effective in improving the accuracy, but they dramatically sacrifice the spee...

partial frames provide a rich context in which to do pointfree structured and unstructured topology. a small collection of axioms of an elementary nature allows one to do much traditional pointfree topology, both on the level of frames or locales, and that of uniform or metric frames. these axioms are sufficiently general to include as examples bounded distributive lattices, $sigma$-frames, $ka...

Serum creatine kinase isoenzyme 2 concentrations (CK 2 mass) were measured in marathon runners during training and 1 and 2 days after a race and compared with values from 36 acute myocardial infarction (AMI) patients whose total CK and (or) CK 2 activities were similar to those of runners in the basal state. During training, runners had CK and CK 2 activities 53% and 43% above reference values,...

The isoforms of CK-MB have recently received attention as potential biochemical markers for the early diagnosis of an acute myocardial infarction. A sensitive (analytical sensitivity = 0.2 ng/ml) immunochemical mass assay for the direct measurement of the CK-MB2 isoform has been developed by us. This assay utilizes a specific monoclonal capture antibody directed against the B-subunit of CK-MB a...

PURPOSE EML4-ALK is a fusion-type protein tyrosine kinase that is generated by inv(2)(p21p23) in the genome of non-small cell lung cancer (NSCLC). To allow sensitive detection of EML4-ALK fusion transcripts, we have now developed a multiplex reverse transcription-PCR (RT-PCR) system that captures all in-frame fusions between the two genes. EXPERIMENTAL DESIGN Primers were designed to detect a...

More than 20 different partner genes with MLL have been cloned from leukemia cells with translocations involving chromosome 11 band q23 (11q23). All reported partner genes fused in-frame to MLL and the fusion cDNA encode chimeric MLL proteins with a significant portion derived from the partner genes. We analyzed one patient with de novo acute monoblastic leukemia with t(11;14)(q23;q24) and iden...