Background and aims. The aim of the present study is to determine the incidence of MTHFR C677 T and A1298C muta-tions in Iranian patients with cleft lip and/or cleft palate. Materials and methods. We screened 61 Iranian patients with cleft lip and/or cleft palate for mutations in the two alleles of MTHFR gene associated with cleft lip and/or palate: A1298C and C677T, using Polymerase Chain Reac...

Two families with non-syndromic cleft lip and cleft palate are described. The linear pattern of inheritance through several generations is difficult to explain by conventional multifactorial models. The pedigrees strengthen the suggestion that a dominantly inherited mutation exists with a major influence on clefting of the lip and palate alone.

Citation: Koul R (2015) Computer processable classification of craniofacial clefts. Different interpretations of the term " Cleft Lip " by clinicians and developmental biologists referred to by Wang et al. (2014) in the introduction of their article on evaluation and integration of disparate classification systems for clefts of the lip, mirrors my observations in an article on nomenclature in c...

The most common oro-facial congenital deformity reported in live newborns is a cleft of the lip, palate, or both. objective this study was to the updates management, and outcomes cases lip and/or palate. PubMed EBSCO Information Services will be chosen as search databases for publications used within study. Topics concerning the updates published English around

Objective: The purpose of this study is to determine the usage of potential teratogenic chemicals among cleft lip and palate mothers attending a multidisciplinary cleft clinic at Komfo Anokye Teaching Hospital (KATH). Method: This is a retrospective study based on records of consecutive patients attending the multidisciplinary cleft clinic at KATH. Mothers of children with cleft lip and palate ...

Ectopic eruption into the nasal cavity is a rare phenomenon and even rarer among cleft lip and palate patients. A case of an intranasal tooth associated with cacosmia in a 5-year-old patient with cleft lip and palate is reported. Several previous surgeries had been performed to correct the patient’s cleft. The patient was evaluated by computed tomography, and the tooth was removed from the nost...

A boy who had previously had a cleft lip and palate repaired and bilateral orchiopexies presented at 16 years of age with delayed puberty. Isolated gonadotrophin deficiency and testicular hyporesponsiveness to human chorionic gonadotrophin were found. The possibility of bilateral cryptorchidism due to gonadotrophin deficiency should be considered in boys with either cleft lip or palate, or both.

The second and final article of this series describes the embryological classifications of cleft lip and palate patients, their usage and deficiencies. Correspondence: Dr. Syed Nasir Shah Head Department of Prosthodontics Sardar Begum Dental College and Hospital, Gandhara University, Academy Town, Peshawar, Pakistan E-mail: [email protected] JKCD June 2012, Vol. 2, No. 2 87 A review of class...

non-syndromic cleft lip with or without cleft palate (nscl/p) is one of the most common congenital abnormalities of the orofacial region with a multifactorial etiology. the present study aimed to investigate the association of two common polymorphisms of methylenetetrahydrofolate reductase (mthfr) gene (c.677c>t and c.1298a>c) with the occurrence of nscl/p in an iranian population.forty-five ns...

PURPOSE The aim of this study was to compare the mandibular hard and soft tissue measurements of unilateral and bilateral cleft lip and palate patients with non-cleft individuals. MATERIALS AND METHODS The study sample comprised of lateral cephalograms of 45 subjects. Sample included 15 non-cleft (NC), 15 unilateral cleft lip and palate (UCLP) and 15 bilateral cleft lip and palate (BCLP) case...