[This corrects the article on p. 1 in vol. 6, PMID: 26870699.].

BACKGROUND Rett Syndrome is a neurodevelopmental disorder almost exclusively affecting females, characterized by a broad clinical spectrum of signs and symptoms and a peculiar course. The disease affects different body systems: nervous, muscolo-skeletal, gastro-enteric. Moreover, part of the symptoms are related to the involvement of the autonomic nervous system. In the Tuscany Rett Center at V...

A case is presented with multiple sites of ectopic pancreatic tissue in the gastro-intestinal tract. The sites were found in the stomach and duodenum, one site of ectopic pancreatic tissue presented with necrotizing pancreatitis. Ectopic pancreatic tissue can be defined as all pancreatic tissue, with no anatomical or vascular continuity with the orthotopic pancreas. The ectopic tissue most like...

In recent years there has been increased interest in infective conditions among the newborn, and it has become evident that the conditions of institutions for the newborn are often such as to favour the occurrence and spread of infection. The staphylococcus is recognized as ubiquitous and a potentially pathogenic organism. Its constant presence in the air and on healthy hands (Devenish and Mile...

SINCE COWPER’S FIRST DESCRIPTION,^ human chronic manganese poisoning has been the subject of many reports and several reviews.2-6 The aim of most publications seems to have been the definition of the clinical picture of this disease in relation to various environmental factors. The clinical picture has consisted of both psychiatric and neurological manifestations, the most crippling of which ha...

Chronic, major vessel thromboembolic pulmonary hypertension (CTEPH), is an uncommon condition which, in the past, was an autopsy curiosity. Advances in diagnostic approaches, surgical techniques and postoperative management have transformed this disorder into a potentially curable form of pulmonary hypertension. The predominant symptom is unexplained dyspnoea on exertion. In patients with this ...

The term "whiplash" commonly refers to symptoms and signs associated with a mechanical event such as a sudden acceleration and deceleration of the neck (due, in the majority of cases, to a road accident), instead of to the mechanism itself. The recent Quebec Classification of Whiplash Associated Disorders (WAD) contributed to define nosographically all the clinical manifestations usually groupe...

UNLABELLED Alopecia areata (AA) is an autoimmune disease that presents as nonscarring hair loss, although the exact pathogenesis of the disease remains to be clarified. Disease prevalence rates from 0.1% to 0.2% have been estimated for the United States. AA can affect any hair-bearing area. It often presents as well demarcated patches of nonscarring alopecia on skin of overtly normal appearance...

August von Wassermann was born in Bavaria just over a century ago, and perhaps it is therefore fitting to report a small group of patients in which serious diagnostic difficulties were resolved with the aid of the complement-fixation test now named after him. We also report these cases in order to draw attention to the fact that neurosyphilis, though uncommon, is not nowadays as rare as some wo...

The most commonly type 1 diabetes mellitus caused by destruction of b cell pancreatic leading to inadequate insulin production. Clinical and laboratory features at the times of diagnosis have been widely studied. We reviewed the clinical appearance of Type 1 Diabetes Mellitus in patients were diagnosed in the Pediatric Department of Saiful Anwar Hospital between 2005 and 2009. The study has bee...