BACKGROUND Breast cancer is the commonest cancer affecting women world wide. Breast cancer is a leading cause of cancer related mortality in Asian countries. Management of breast cancer depends on several tumour-related and patient related factors. HER-2/neu over-expression has been associated with a poor prognosis in breast cancer. We assessed HER-2/neu over expression pattern in unselected br...

BACKGROUND AND OBJECTIVES The therapy and outcome of HIV infection have dramatically changed over the last 15 years, resulting in a change in renal complications. This study analyzed the characteristics of HIV-infected patients and biopsy-proven tubulointerstitial nephropathies to define disease patterns and therapeutic implications. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS A clinico-pat...

Pancytopenia is a reduction in all the three cellular elements of blood; exists in adult when the hemoglobin level is less than 10g/dL, total leukocyte count is less than 4x109/L, and platelet count is less than 150x109/L.1 Pancytopenia can be due to decrease in hemopoietic cell production, ineffective haemopoiesis or peripheral destruction of the cells. The haemopoietic cell production can be ...

Ewing sarcoma is the second most common involving bones in children and adolescents. Published data on clinical features, morphology, translocation follow-up of patients with from India, sparse. Objectives this study were to analyse clinico-pathologic features compare status, BCoR immunohistochemistry, treatment survival. 406 cases diagnosed Department Pathology, Christian Medical College, Vell...

Introduction: One of the most important regulators immune response is programmed death receptor 1 (PD-1) and its interaction with ligand (PD-L1), which negatively influences response. Objectives: This study aims to clarify PD-L1 expression levels associated tumor infiltrating lymphocytes (TILs) in patients metastatic breast cancer, assess their influence on prognosis these association clinico-p...

In a retrospective three year study 13 cases of xanthogranulomatous cholecystitis (XGC) (seven female, six male) were found in 724 gallbladders (1 8%), an estimated incidence of 1 7 cases per 1O00000 population per annum. Symptoms often began with an episode of acute cholecystitis and persisted for up to five years. There was extension of xanthogranulomatous tissue into adjacent organs in nine ...

PURPOSE To evaluate conditional survival among patients with surgically resected stage I-IIIa lung adenocarcinoma and identify changes in prognostic contributions for various prognostic factors over time. PATIENTS AND METHODS We performed conditional survival analysis at each t0 (=0, 1, 2, 3, 4, 5 years) for 723 consecutive patients who underwent surgical resection for lung adenocarcinoma, st...

Twenty-five cases of mucoepidermoid carcinoma of the salivary glands were studied with respect to clinico-pathologic features, prognostic factors, and c-erbB-2 oncoprotein expression. Fourteen cases were located in parotid glands, 2 in submandibular glands and 9 in minor salivary glands. Fourteen patients were confirmed to have local recurrences, 6 patients manifested systemic metastases, and 1...

The aim of this study was to assess surgical outcome at radical prostatectomy (RP) in Korean men with a serum prostate-specific antigen (PSA) level of 2.5 to 3.0 ng/mL and compared with those of patients who had a PSA level of 3.0-4.0 and 4.0-10.0 ng/mL. We retrospectively compared clinico-pathological characteristics and biochemical recurrence (BCR) risk in patients with PSA level of 2.5-3.0 (...