histiocytic necrotizing lymphadenitis or kikuchi's disease is a rare, benign condition of unknown etiology, which is usually characterized by cervical lymphadenopathy and fever. this disease is rarely associated with systemic lupus erythematosus. here we describe, for the first time in iran, a patient who developed systemic lupus erythematosus about 3 years after the initial diagnosis of kikuch...

background: systemic lupus erythematosus is a kind of multi-system autoimmune disorder with unknown aetiology and it produces antibodies against various tissues. case presentation:the patient wasa 44-year-old woman with a history of systemic lupus erythematosus for approximately five years, along with underlying diseases including peptic ulcers, asthma, hypertension and diabetes in the past 10 ...

Isolated brain stem lesions presenting with acute neurologic findings create a major diagnostic dilemma in children. Although the brain stem is frequently involved in ADEM, solitary brain stem lesions are unusual. We performed a retrospective review in 6 children who presented with an inflammatory lesion confined to the brain stem. Two children were diagnosed with connective tissue disorder, CN...

A 70-year-old man presented with complaints of rapid cognitive decline and new onset leukopenia. The patient had a 17-year history of refractory seizures. Detailed review of symptoms and investigations revealed the patient met American College of Rheumatology (ACR) diagnostic criteria for systemic lupus erythematosus (SLE). The patient had high titer ANA with a strongly positive dsDNA. Immunosu...

A Central nervous system (CNS) hemorrhage is bleeding in or around the brain and spinal cord. Reasons of CNS hemorrhage include high blood pressure, cancers, drug abuse, abnormally weak blood vessels that leakage, and trauma. Regression of CNS bleeding was confirmed to be relatively repetitive in patients with severe FV, FX, FVII and FXIII deficiencies. Generally in CNS hemorrhage, radiological...

We present a case of a patient with systemic vasculitis suffering--besides heart, skin and gastrointestinal lesions--from the rarely reported involvement of the central nervous system. Even though the diagnosis could not be ascertained precisely, immunosuppressive therapy led to prompt regression of symptoms including initially present neurologic manifestations.

how to cite this article: khoddami m, akbarzadeh a, mordai a, bidari zerehpoush f, alipour h, samadzadeh s, alipour b.diagnostic accuracy of frozen section of central nervous system lesions: a 10-year study. iran j child neurol. 2015 winter;9(1):25-30.   abstract objective definitive diagnosis of the central nervous system (cns) lesions is unknown prior to histopathological examination. to dete...

abstract objective : the policy makers and social managers need some criteria for building up the appropriate health status of the community and observe the equity and equality on it. they have to know the burden of diseases as a main determining factor for decision making, planning and programming. disability adjusted life years (dalys) is a criteria which shows the wasted life time due to ear...

objective: premna integrifolia linn (family: verbenaceae) synonym of premna serratifolia has tremendous medicinal value. preliminary pharmacological studies were performed on the methanolic extract of premna integrifolia (mepi) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. materials and methods: neuropharmacology study was done by open field and hole cro...

OBJECTIVES To investigate change in psychiatric disorder and change in cognitive function in patients with systemic lupus erythematosus (SLE) assessed on two occasions two years apart. METHODS A prospective cohort study of 49 patients with SLE using standardised psychiatric and clinical research methods. RESULTS The point prevalence of psychiatric disorder (20% and 24%), and of cognitive im...