Traumatic brain injury (TBI) is the most common cause of death and disability in young adults, yet the molecular mechanisms that follow TBI are poorly understood. We previously reported a perturbation in iron (Fe) levels following TBI. Here we report that the distribution of cobalt (Co) is modulated in post-mortem human brain following injury. We also investigated how the distribution of other ...

1. The preparation and characterization of manganese, iron, cobalt, nickel, copper and zinc metalloporphyrins is described. Ferrihaem was also esterified with pyrid-4-ylpropanol and the derivative characterized as the diester. 2. Complexes of these various porphyrins, as well as protoporphyrin IX, with apomyoglobin were formed and the resulting artificial myoglobins characterized. 3. Very littl...

Cobalt (Co) doped Zinc Oxide (ZnO) thin films, containing different amountof Cobalt nanoparticles as the Co doping source, deposited by the sol–gel spin coatingmethod onto glass via annealing temperature at 400˚C, have been investigated by opticalcharacterization method. The effect of Co incorporation on the surface morphology wasclearly observed from scanning electron microscopy (SEM) images. ...

We describe a subject who developed asthma symptoms 2 yrs after being employed at a plant where metals were galvanized in heated zinc. The subject was not atopic. Baseline spirometry was normal three months after he left work but there was mild bronchial hyperresponsiveness to methacholine. Monitoring of forced expiratory volume in one second (FEV1) during a day at work showed a maximum fall in...

This study demonstrates the effectiveness of heat treatment in optimizing the magneticproperties of cobalt ferrite, compared to other methods such as cation substitution. It also shows how the magnetic properties of the heat treated cobalt ferrite vary under differenttemperature conditions. Saturation magnetization increased more due to heat treatment than due to Zn-substitution; a cation subst...

INTRODUCTION Accumulation of trace elements occurs in conditions of decreased kidney function. In some conditions, increased trace elements can have toxic features. On the other hand, studies are showing that concentration of some trace elements could be decreased in ERSD patients as well. The most important factor affecting trace element concentration in ERSD patients is the degree of renal fa...

Extracts of human articular cartilage contain proteases capable of degrading the proteoglycan component of cartilage matrix at neutral and acid pH. These enzymes have been partially purified by ion exchange chromotography and characterized by disc electrophoresis, inhibition patterns, and action of proteoglycan. Three distinct metalloproteases are described. A neutral protease that digests prot...

A study of the effect of certain metals on the prevention of nutritional anemia in the rat has been reported in the preceding paper (4). Animals receiving a mixture of manganese, cobalt, nickel, and zinc with iron developed a progressive anemia and died, whereas those receiving the same mixture with iron and copper developed an abnormally high hemoglobin value at the age of 7 to 9 weeks. After ...

The Czc system of Ralstonia sp. strain CH34 mediates resistance to cobalt, zinc, and cadmium through ion efflux catalyzed by the CzcCB(2)A cation-proton antiporter. The CzcD protein is involved in the regulation of the Czc system. It is a membrane-bound protein with at least four transmembrane alpha-helices and is a member of a subfamily of the cation diffusion facilitator (CDF) protein family,...

In this work we characterize an alcohol dehydrogenase (ADH) from the hyperthermophilic archaeon Pyrobaculum aerophilum (PyAeADHII). We have previously found that PyAeADHII has no activity when standard ADH substrates are used but is active when α-tetralone is used as substrate. Here, to gain insights into enzyme function, we screened several chemical libraries for enzymatic modulators using an ...