نتایج جستجو برای: cochlear damage
تعداد نتایج: 241120 فیلتر نتایج به سال:
Robotic assistance in the context of lateral skull base surgery, particularly during cochlear implantation procedures, has been the subject of considerable research over the last decade. The use of robotics during these procedures has the potential to provide significant benefits to the patient by reducing invasiveness when gaining access to the cochlea, as well as reducing intracochlear trauma...
Keratoconjunctivitis sicca, conjunctival scarring, fibrosis, metaplasia, and shrinkage developed in 27 patients as an adverse reaction to practolol. Rashes, nasal and mucosal ulceration, fibrous or plastic peritonitis, pleurisy, cochlear damage, and secretory otitis media also occurred in some cases. Three patients suffered profound visual loss though most retained good vision. Symptoms and sig...
Recent work suggests that hair cells are not the most vulnerable elements in the inner ear; rather, it is the synapses between hair cells and cochlear nerve terminals that degenerate first in the aging or noise-exposed ear. This primary neural degeneration does not affect hearing thresholds, but likely contributes to problems understanding speech in difficult listening environments, and may be ...
Before outlining some important directions for cochlear implant research in the Third Millennium, it is worth reviewing a few of the achievements of the Second Millennium. As recently as the 1960s and 1970s, many scientists and clinicians claimed that successful cochlear implants were not possible in the foreseeable future. However, over the last 30 years, many of their objections have been ove...
OBJECTIVE Magnetic resonance imaging is a routine investigation in cases of asymmetric sensorineural hearing loss, but it is not routinely used to investigate bilateral sensorineural hearing loss. METHOD This case report illustrates the benefits of magnetic resonance image scanning in the latter patient group. RESULTS A 53-year-old man with rapidly progressive, symmetrical, bilateral, senso...
Common causes of hearing loss in humans - exposure to loud noise or ototoxic drugs and aging - often damage sensory hair cells, reflected as elevated thresholds on the clinical audiogram. Recent studies in animal models suggest, however, that well before this overt hearing loss can be seen, a more insidious, but likely more common, process is taking place that permanently interrupts synaptic co...
Time-domain simulations of the response to click of a human ear show that, if the cochlear amplifier gain (CAG) is a smooth function of basilar-membrane (BM) position, the filtering performed by a middle ear with an irregular (non-smooth) transfer function suffices to produce irregular and long-lasting residual BM oscillations at selected frequencies. Feeding back to the middle ear through hydr...
A deficiency in pejvakin, a protein of unknown function, causes a strikingly heterogeneous form of human deafness. Pejvakin-deficient (Pjvk(-/-)) mice also exhibit variable auditory phenotypes. Correlation between their hearing thresholds and the number of pups per cage suggest a possible harmful effect of pup vocalizations. Direct sound or electrical stimulation show that the cochlear sensory ...
BACKGROUND A single drilled tunnel from the lateral mastoid cortex to the cochlea via the facial recess is essential for minimally invasive cochlear implant surgery. This study aimed to explore the safety profile of this kind of new image-guided and bi-planar device-assisted surgery procedure in vitro. METHODS Image-guided minimally invasive cochlear implantations were performed on eight cada...
The protective effects of cochlear pre-conditioning have been documented, especially in regard to noise. Conditioning with moderate-intensity noise toughens the ear and makes it more resistant to damage from high-level noise exposures. The goal of the project was to determine whether cochlear pre-conditioning is effective in protecting against the ototoxic effects of cisplatin. Pre-conditioning...
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