نتایج جستجو برای: cognitive aging

تعداد نتایج: 343878  

2009
Corinna E. Löckenhoff Antonio Terracciano Marleen De Bolle

College students (N = 3,435) in 26 cultures reported their perceptions of agerelated changes in physical, cognitive, and socioemotional areas of functioning and rated societal views of aging within their culture. There was widespread cross-cultural consensus regarding the expected direction of aging trajectories with (1) perceived declines in societal views of aging, physical attractiveness, th...

2012
Thomas C. Foster

With the prolonged lifespan brought about by medical advances, attention is increasingly focused on problems that arise from such longevity, including diseases that tend to occur in elderly populations. Despite progress on health related issues, little progress has been made with respect to the treatment of cognitive decline that can accompany the aging process. In humans, age-related impairmen...

2014
Robert Clarke Derrick Bennett Sarah Parish Sarah Lewington Murray Skeaff Simone JPM Eussen Catharina Lewerin David J Stott Jane Armitage Graeme J Hankey Eva Lonn J David Spence Pilar Galan Lisette C de Groot Jim Halsey Alan D Dangour Rory Collins Francine Grodstein

BACKGROUND Elevated plasma homocysteine is a risk factor for Alzheimer disease, but the relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain. OBJECTIVE The aim was to assess the effects of treatment with B vitamins compared with placebo, when administered for several years, on composite domains of cognitive function, global cognitive function, and cognitive agin...

2014
Robert Clarke Derrick Bennett Sarah Parish Sarah Lewington Murray Skeaff Simone JPM Eussen Catharina Lewerin David J Stott Jane Armitage Graeme J Hankey Eva Lonn J David Spence Pilar Galan Lisette C de Groot Jim Halsey Alan D Dangour Rory Collins Francine Grodstein

Background: Elevated plasma homocysteine is a risk factor for Alzheimer disease, but the relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain. Objective: The aim was to assess the effects of treatment with B vitamins compared with placebo, when administered for several years, on composite domains of cognitive function, global cognitive function, and cognitive agin...

Journal: :Neurobiology of Aging 2016
Sarah M. Neuner Benjamin P. Garfinkel Lynda A. Wilmott Bogna M. Ignatowska-Jankowska Ami Citri Joseph Orly Lu Lu Rupert W. Overall Megan K. Mulligan Gerd Kempermann Robert W. Williams Kristen M.S. O'Connell Catherine C. Kaczorowski

An individual's genetic makeup plays an important role in determining susceptibility to cognitive aging. Identifying the specific genes that contribute to cognitive aging may aid in early diagnosis of at-risk patients, as well as identify novel therapeutics targets to treat or prevent development of symptoms. Challenges to identifying these specific genes in human studies include complex geneti...

Journal: :Psychophysiology 2016
David Weiss Mona Weiss

Older adults are more likely than younger adults to experience stress when confronted with cognitive challenges. However, little is known about individual differences that might explain why some older adults exhibit stronger stress responses than others. We examined the interplay of two social-cognitive factors to explain older adults' cortisol reactivity: (1) subjective social status, and (2) ...

Journal: :Journal of Alzheimer's disease : JAD 2010
Kirk R Daffner

Promoting successful cognitive aging is a topic of major importance to individuals and the field of public health. This review presents a coherent framework not only for evaluating factors, protective activities, and enhancing agents that have already been proposed, but also ones that will be put forward in the future. The promotion of successful cognitive aging involves the dual goals of preve...

2012
Yeon Kyung Chi Tae Hui Kim Ji Won Han Seok Bum Lee Joon Hyuk Park Jung Jae Lee Jong Chul Youn Jin Hyung Jhoo Dong Young Lee Ki Woong Kim

OBJECTIVE We investigated neuropsychological markers that can be used to discriminate pathological cognitive aging from normal cognitive aging. METHODS We administered frontal lobe function tests including the Wisconsin Card Sorting Test (WCST), digit span test, lexical fluency test, fixed condition design fluency test, and Trail Making Test B (TMT-B) to 92 individuals with pathological cogni...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
Timothy R Chapman Ruth M Barrientos Jared T Ahrendsen Steven F Maier Susan L Patterson

Variability in cognitive functioning increases markedly with age, as does cognitive vulnerability to physiological and psychological challenges. Exploring the basis of this vulnerability may provide important insights into the mechanisms underlying aging-associated cognitive decline. As we have previously reported, the cognitive abilities of aging (24-month-old) F344 x BN rats are generally goo...

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