Acclimatization to hypoxia has minimal effect on maximal O2 uptake (Vo2 max). Prolonged hypoxia shows reductions in cardiac output (Q), maximal heart rate (HR-max), myocardial beta-adrenoceptor (beta-AR) density, and chronotropic response to isoproterenol. This study tested the hypothesis that exercise training (ET), which attenuates beta-AR downregulation, would increase HRmax and Q of acclima...

In the face of climate change, the persistence of cold-adapted species will depend on their adaptive capacity for physiological traits within and among populations. The lake trout (Salvelinus namaycush) is a cold-adapted salmonid and a relict from the last ice age that is well suited as a model species for studying the predicted effects of climate change on coldwater fishes. We investigated the...

Climate change is expected to increase heat-related and decrease cold-related mortality. The extent of acclimatization of the population to gradually-changing thermal conditions is not well understood. We aimed to define the relationship between mortality and temperature extremes in different age groups in the Helsinki-Uusimaa hospital district in Southern Finland, and changes in sensitivity of...

Global climate change (GCC) is the most widespread environmental peril facing tropical coral reefs, yet the capacity of scleractinian corals to survive the challenge is not well understood. Acclimatization is a primary mechanism by which organisms match their physiology in a timely and beneficial way to a rapidly changing environment, and so it is not surprising that the question ‘can corals ac...

Exposure to acute high-altitude hypoxia is associated with an increase in cerebral blood flow (CBF) as a consequence of low arterial O2 tension. However, in response to high altitude acclimatization, CBF returns to levels similar to those at sea level, and tissue blood flow is maintained by an increase in angiogenesis. Of consequence, dysregulation of the acclimatization responses and CBF can r...

Cold acclimation of hamsters was found to result in an increase in cytochrome concentration relative to ATPase activity in brown adipose tissue mitochondria, but not in liver mitochondria. These data lend support to the hypothesis that the uncoupled respiration characteristic of non-shivering thermogenesis is the result of an adaptive change in the composition of brown adipose tissue mitochondr...

The seasonal variation of sweating responses under identical heat stress was investigated to make clear the seasonal acclimatization in daily human life on the experiments. The heat stress of 33 degrees C air temperature, 50% relative humidity laid in the experiments was chosen as a usual daytime condition in summer in metropolitan cities such as Tokyo and Osaka. Five subjects were exposed unde...

Personnel who travel to areas with a hot climate (WBGT > 27°C) may suffer from the heat (physiological strain, thermal discomfort, increased probability of heat illness), making them partially or fully inoperative. Performing physical activities during heat acclimatization is known to improve this process (i.e., improve measures of acclimatization for the same duration of acclimation). However,...

Following the dispersal out of Africa, where hominins evolved in warm environments for millions of years, our species has colonised different climate zones of the world, including high latitudes and cold environments. The extent to which human habitation in (sub-)Arctic regions has been enabled by cultural buffering, short-term acclimatization and genetic adaptations is not clearly understood. ...

To prepare for extremes of heat, cold or low partial pressures of oxygen (O2), humans can undertake a period of acclimation or acclimatization to induce environment-specific adaptations, e.g. heat acclimation (HA), cold acclimation (CA), or altitude training. While these strategies are effective, they are not always feasible due to logistical impracticalities. Cross-adaptation is a term used to...