The combination of anemia in malarial infestations ranges from nutritional deficiency to marrow suppression. An immune hemolytic anemia in Plasmodium falciparum malaria is also a part of this wide-ranging spectrum. But the co-existence of cold agglutinins in a Plasmodium falciparum malaria has only sporadically been reported in literature. We present a case of a patient with falciparum malaria ...

INTRODUCTION There are a number of pre-analytical and analytical factors, which cause false results in the complete blood count. The present case identifies cold agglutinins as the cause for the mismatch between hematocrit and hemoglobin values. MATERIALS AND METHODS 70-year old female patient had a history of cerebrovascular diseases and rheumatoid arthritis. During routine laboratory examin...

Primary cold agglutinin disease (CAD) is an infrequent lymphoproliferative disorder without any efficient conventional therapy. Its prevalence is comprised from 1/70000 to 1/350000. 1 It may give severe symptoms and reduced quality of life. Because of the haemagglutination most patients experience pallor, acrocyanosis and Raynaud's phenomenon during slight to moderate cold exposure. 2 It is a s...