Background and Objective: This study was aimed to evaluate the collagen fibers qualitatively and its correlation with microvascular density in various grades of oral submucous fibrosis (OSMF).   Material and Methods: The present study comprised of total 40 cases of oral submucous fibrosis. Picrosirius red staining was done on all the specimens’ sections. ...

Introduction: Hedera helix is an evergreen plant used in treatment of wounds in the Iranian folk medicine. One of the main stages in wound healing process is, the proliferative phase in which fibroblasts proliferate within the wounds and produce extracellular matrix. Collagen is the main constituent of extracellular matrix. So the aim of this study was to evaluate the effect of Hedera helix alc...

Introduction The Joint Hypermobility Syndrome (JHS) is a multi-system inherited connective tissue disorder caused by defective fibrous tissue matrix proteins such as collagen. Joint hypermobility has been occurred more frequently in children, with diminishing occurrence as age increases in population studies. The prevalence of hypermobility in children has been reported to be between 2.3 and 30...

Osteogenesis imperfecta (OI) is an inherited disorder of the connective tissues caused by abnormalities in collagen formation. OI may present many challenges to the anesthesiologist. A literature review reveals a wide range of implications, from basic positioning to management of the difficult airway. We present the anesthetic management of a 25-year-old gravid woman with OI, fetal demise, and ...

INTRODUCTION Osteogenesis imperfecta (OI) is a genetic disorder of type I collagen that results in bone fragility. This fragility is believed to stem from a combination of bone mass deficiency and compromised bone material properties [13]. Little data, however, is yet available to describe bone material properties in individuals with OI. This study presents the first characterization of bone ma...

Porokeratosis, a keratinization and fibroblast cutaneous disorder, is a progressive disease with limited treatment options. We describe a case of linear porokeratosis that responded favorably to a series of 585 nm pulsed dye laser treatments. In addition to its vascular specificity, the pulsed dye laser presumably produces a direct effect on collagen, as well as an indirect effect on histamine ...

Osteogenesis imperfecta is a collagen related disorder characterized by increased bone fragility and low bone mass. The important oral finding in osteogenesis imperfect is the presence of dentinogenesis imperfecta. This article presents a case of osteogenesis imperfecta (type IV B) with dentinogenesis imperfecta where a 7-year-old girl had opalacent primary teeth associated with severe bone def...

background: nicotine can pass through placental blood barrier and accumulate in the developing organs of fetus. also, entering the breast milk, nicotine can have an effect on the neonates. investigations have showed that collagen iv is one of the most important micro vessels basement membrane components. objective:  in this study, the effect of maternal nicotine exposure in pre and postnatal pe...