The current practice of treating cervical cancer with surgery or radiation alone has been challenged by the recent information from the National Cancer Institute regarding concurrent chemoradiation for cervical cancer. Results from each of five randomized phase III trials show an overall survival advantage of 30% — plus acceptable toxicity — for cisplatin-based therapy given concurrently with r...

Locally advanced head and neck cancers are usually treated with concurrent chemoradiation. The residual nodes after chemoradiation in such patients are a common scenario, but the further investigation and treatment options in form of neck dissection are still not very clear. This review focuses on the current state of available evidence in literature for management of such patients and directs ...

esophageal cancer is one of the most common malignancies with a growing occurrence . it presently ranks ninth among the most frequent cancers in the world and the sixth leading cause of death from cancer . for a variety of reasons, the mainstream of patients with esophageal cancer is actually not suitable for esophagectomy. more than 50% have locally advanced unresectable or metastatic tumors a...

PURPOSE Elderly patients (65 or older) with cervical cancer often receive suboptimal radio-chemotherapy. Intensity-modulated radiotherapy (IMRT) may improve tolerance to treatment in this setting. This study was designed to compare the treatment-related toxicities and compliance with treatment in patients of cervical cancer treated definitively with RapidArc IMRT in our institute. METHODS AND...

BACKGROUND: The standard of care for esophageal cancer has historically been surgical resection. However, survival following surgical treatment of esophageal cancer remains poor. In inoperable patients, both radiation therapy and chemotherapy alone and in combination have been used with some success. Consequently, these therapies have been utilized in the neoadjuvant setting to improve palliati...

There has been growing interest in utilizing information from cone-beam computed tomography (CBCT) to help guide both treatment delivery and prognosis. In this assessment of locally advanced unresectable stage III non-small cell lung cancer (NSCLC) treated with definitive chemoradiation, we aimed determine the survival advantage associated using CBCT measure tumor regression. Patient, tumor, ch...

Objective: The objective of this study was to identify high risk factors for survival in locally advanced rectal cancer patients with ypT0-2N0 after neoadjuvant chemoradiation. Methods: In this study, Surveillance, Epidemiology, and End Results Program (SEER)-registered rectal cancer patients, and patients from Fudan University Shanghai Cancer Center (FUSCC) after preoperative chemoradiation we...

Glioblastoma multiforme (GBM) is the most common primary brain tumors, accounting for 1520% of all intracranial tumors. It is one of the most lethal tumors of the central nervous system with a median survival from diagnosis on the order of 6 to 18 months. Despite aggressive resection and chemoradiation, the tumor always recurs. Magnetic Resonance (MR) imaging is an essential component in the di...

PURPOSE To evaluate the differences in the outcomes of patients with stage II and IIIa non-small cell lung cancer (NSCLC) treated with either 131I-labeled mouse/human chimeric monoclonal antibody against intracellular DNA exposed in necrotic and degenerating regions of tumors (131I-chTNT-mediated radioimmunotherapy) combined with percutaneous microwave coagulation therapy (PMCT) guided by compu...